Guanfacine Pregnancy Warnings
Animal studies revealed reduced fetal survival at doses that produced maternal toxicity. There are no controlled data in human pregnancy.
US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
UK: Use is not recommended.
US: This drug should be used during pregnancy only if clearly needed.
US FDA pregnancy category: B
Comments: Adequate methods of contraception should be encouraged.
See references
Guanfacine Breastfeeding Warnings
UK: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
US: Other agents may be preferred; otherwise, caution is recommended.
Excreted into human milk: Unknown
Excreted into animal milk: Yes
Comments: The effects in the nursing infant are unknown.
See references
