Use during pregnancy is contraindicated

AU TGA pregnancy category: C
US FDA pregnancy category: X

There are no adequate animal studies. There are no controlled data in human pregnancy. Based on its pharmacology and reproductive studies conducted with similar products, an increase in embryonic resorptions and post-implantation loss may be expected at clinically relevant doses.

AU TGA pregnancy category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible. Accompanying texts should be consulted for further details.

US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

See references

AU, UK: Contraindicated
US: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

See references