Asthmanefrin Pregnancy Warnings
Animal studies are not available. There are no controlled data in human pregnancy.
US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.
The manufacturer makes no recommendation regarding use during pregnancy.
US FDA pregnancy category: Not assigned
Comments:
-There is no data on use of racepinephrine during pregnancy.
-Racepinephrine is a racemic mixture of both the D- and L-isomers of epinephrine; epinephrine contains only the L-isomer.
-Epinephrine freely crosses the placenta and may be teratogenic in some species, but does not appear to be teratogenic in humans.
-In the Collaborative Perinatal Project, there was a statistically significant association between the use of epinephrine during pregnancy and major and minor malformations, including inguinal hernia.
See references
