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Home > Drugs > Minerals and electrolytes > Magnesium chloride (injection) > Magnesium Chloride Injection Prescribing Information
Minerals and electrolytes
https://themeditary.com/pro/magnesium-chloride-injection-prescribing-information-15321.html

Magnesium Chloride Injection Prescribing Information

Drug Detail:Magnesium chloride (injection) (Magnesium chloride (injection) [ mag-nee-see-um-kloe-ride ])

Drug Class: Minerals and electrolytes

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Magnesium Chloride Injection Description

Magnesium Chloride Injection is a sterile solution of Magnesium Chloride Hexahydrate in Water for Injection q.s. Each mL contains Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection, q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2.951 mOsm/mL.

Contains 1.97 mEq of Mg++ and Cl- per mL.

The structural formula is MgCl2•6H2O

ACTIONS

Magnesium is the second most plentiful cation within cellular fluids. It is an important activator of many enzyme systems and deficits are accompanied by a variety of functional disturbances.

Indications and Usage for Magnesium Chloride Injection

As an electrolyte replenisher in magnesium deficiencies.

Contraindications

Magnesium Chloride Injection should not be administered if there is renal impairment, marked myocardial disease or to comatose patients.

Related/similar drugs

lisinopril, metoprolol, aspirin, clopidogrel, Plavix, Brilinta, magnesium oxide

Warnings

Do not use if a precipitate is present.

Precautions

The usual precautions for parenteral administration should be observed. Administer with caution if flushing and sweating occurs. A preparation of a calcium salt should be readily available for intravenous injection to counteract potential serious signs of magnesium intoxication. As long as deep tendon reflexes are active it is probable that the patient will not develop respiratory paralysis. Respiration and blood pressure should be carefully observed during and after administration of Magnesium Chloride Injection.

Pregnancy

Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed.

Adverse Reactions/Side Effects

Flushing, sweating, sharply lowered blood pressure, hypothermia, stupor and ultimately respiratory depression.

Magnesium Chloride Injection Dosage and Administration

For intravenous infusion: 4 grams in 250 mL of 5% Dextrose Injection, at a rate not exceeding 3 mL per minute. Serum magnesium levels should serve as a guide to continued dosage.

USUAL DOSAGE RANGE

1 to 40 grams daily.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

How is Magnesium Chloride Injection supplied

Magnesium Chloride Injection 200 mg/mL (20% w/v).

NDC 67457-134-50
50 mL Multiple-Dose Vial. Individually boxed.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled
Room Temperature.]

Manufactured for:
Mylan Institutional LLC
Morgantown, WV 26505

Manufactured by:
Mylan Institutional
Galway, Ireland

1084L101
Revised: 10/2021
MI:MAGNIJ:R4

PRINCIPAL DISPLAY PANEL - 200 mg/mL

NDC 67457-134-50 50 mL

Magnesium
Chloride
Injection

200 mg/mL
(20% w/v)

2.951 mOsm/mL

For Intravenous Use After
Dilution

Rx only Multiple-Dose Vial

Each mL contains: Magnesium
Chloride Hexahydrate 200 mg,
Sodium Chloride 9 mg, Benzyl
Alcohol 1% as a preservative,
Water for Injection q.s. pH adjusted
with Hydrochloric Acid and/or
Sodium Hydroxide.

Total osmolarity equivalent to
2.951 mOsm/mL.

Contains 1.97 mEq of Mg++ and CI¯
per mL.

WARNING: DO NOT USE IF A
PRECIPITATE IS PRESENT.

Store at 20° to 25°C (68° to 77°F).
[See USP Controlled Room
Temperature.]

Usual Dosage: See accompanying
prescribing information.

Manufactured for:
Mylan Institutional LLC
Morgantown, WV 26505 U.S.A.

Manufactured by:
Mylan Institutional
Galway, Ireland

MI:134:1C:R5

Mylan.com

Magnesium Chloride Injection 200 mg/mL Carton Label
MAGNESIUM CHLORIDE
magnesium chloride injection
Product Information
Product TypeHUMAN PRESCRIPTION DRUGItem Code (Source)NDC:67457-134
Route of AdministrationINTRAVENOUS
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
MAGNESIUM CHLORIDE (UNII: 02F3473H9O) (MAGNESIUM CATION - UNII:T6V3LHY838) MAGNESIUM CHLORIDE200 mg in 1 mL
Inactive Ingredients
Ingredient NameStrength
SODIUM CHLORIDE (UNII: 451W47IQ8X) 9 mg in 1 mL
BENZYL ALCOHOL (UNII: LKG8494WBH) 10 mg in 1 mL
WATER (UNII: 059QF0KO0R)
HYDROCHLORIC ACID (UNII: QTT17582CB)
SODIUM HYDROXIDE (UNII: 55X04QC32I)
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:67457-134-501 in 1 CARTON03/14/2013
150 mL in 1 VIAL, MULTI-DOSE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
Unapproved drug other03/14/2013
Labeler - Mylan Institutional LLC (790384502)

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