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Home > Drugs > Alpha-adrenoreceptor antagonists > Silodosin > Silodosin Side Effects
Alpha-adrenoreceptor antagonists

Silodosin Side Effects

Summary

Commonly reported side effects of silodosin include: retrograde ejaculation. Continue reading for a comprehensive list of adverse effects.

Applies to silodosin: oral capsule.

Serious side effects of Silodosin

Along with its needed effects, silodosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking silodosin:

Less common

  • Chills
  • cold sweats
  • confusion
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

Incidence not known

  • Clay-colored stools
  • dark urine
  • fever
  • headache
  • hives, itching, rash
  • loss of appetite
  • nausea
  • pinpoint red or purple spots on the skin
  • skin blisters
  • stomach pain
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin

Other side effects of Silodosin

Some side effects of silodosin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Change or problem with discharge of semen

Less common

  • Diarrhea
  • muscle aches
  • sore throat
  • stuffy or runny nose

For Healthcare Professionals

Applies to silodosin: oral capsule.

General

The most common adverse reaction was retrograde ejaculation.[Ref]

Genitourinary

Very common (10% or more): Retrograde ejaculation (28.1%)

Common (1% to 10%): Prostate-specific antigen (PSA) increased

Uncommon (0.1% to 1%): Priapism[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, nasal congestion, sinusitis, rhinorrhea

Postmarketing reports: Pharyngeal edema[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache

Uncommon (0.1% to 1%): Syncope[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, abdominal pain

Postmarketing reports: Swollen tongue[Ref]

Cardiovascular

Common (1% to 10%): Orthostatic hypotension[Ref]

Other

Common (1% to 10%): Asthenia[Ref]

Psychiatric

Common (1% to 10%): Insomnia[Ref]

Ocular

Frequency not reported: Intraoperative floppy iris syndrome[Ref]

Dermatologic

Postmarketing reports: Toxic skin eruption, purpura, skin rash, pruritus, urticaria[Ref]

Hepatic

Postmarketing reports: Jaundice, hepatic function impaired, transaminases increased[Ref]

Immunologic

Postmarketing reports: Allergic-type reactions[Ref]

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