Note: This document contains side effect information about lenacapavir. Some dosage forms listed on this page may not apply to the brand name Sunlenca.
Applies to lenacapavir: oral tablet. Other dosage forms:
- subcutaneous solution
Serious side effects of Sunlenca
Along with its needed effects, lenacapavir (the active ingredient contained in Sunlenca) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lenacapavir:
Incidence not known
- Dark urine
- fever
- inability to move the arms and legs
- joint pain
- light-colored stools
- muscle tenderness, weakness, or pain
- nausea and vomiting
- skin rash
- sudden numbness and weakness in the arms and legs
- unusual tiredness or weakness
- upper right abdominal or stomach pain
- weight loss
- yellow eyes and skin
For Healthcare Professionals
Applies to lenacapavir: oral tablet, subcutaneous solution.
Gastrointestinal
Common (1% to 10%): Nausea[Ref]
General
The most common adverse reactions reported in at least 3% patients were nausea and injection site reactions.[Ref]
Hepatic
Common (1% to 10%): Increased alanine aminotransferase (ALT), increased aspartate aminotransferase (AST), increased direct bilirubin[Ref]
Local
Four percent patients experienced Grade 3 ISRs (erythema, pain, swelling)[Ref]
Very common (10% or more): Injection site reactions (65%) [include swelling (36%), pain (31%), erythema (31%), nodule (25%), induration (15%), pruritus (6%), extravasation (3%) and mass (3%)][Ref]
Metabolic
Common (1% to 10%): Glycosuria, hyperglycemia, proteinuria[Ref]
Musculoskeletal
Very common (10% or more): Increased creatinine (13%)[Ref]
