Note: This document contains side effect information about methyltestosterone. Some dosage forms listed on this page may not apply to the brand name Testred.

Applies to methyltestosterone: oral capsules, oral tablets.

Side effects include:

Males: Gynecomastia, frequent or persistent penile erections.

Females: Amenorrhea, other menstrual irregularities, inhibition of gonadotropin secretion, virilization (e.g., deepening of the voice, clitoral enlargement).

For Healthcare Professionals

Applies to methyltestosterone: compounding powder, oral capsule, oral tablet.

General

The more commonly reported adverse effects of androgen therapy in males is gynecomastia and excessive frequency and duration of penile erections; in women, virilization including voice deepening and clitoral enlargement.^[Ref]

Cardiovascular

Frequency not reported: Edema with or without congestive heart failure, myocardial infarction, stroke

Postmarketing reports: venous thromboembolic events, including deep vein thrombosis (DVT)^[Ref]

Endocrine

Frequency not reported: Gynecomastia, virilization (women), hirsutism^[Ref]

Hepatic

Rare (less than 0.1%): Peliosis hepatic

Frequency not reported: Cholestatic jaundice, altered liver function^[Ref]

Genitourinary

Frequency not reported: Amenorrhea, menstrual irregularities, excessive frequency and duration of penile erections, oligospermia, increased or decreased libido^[Ref]

Metabolic

Frequency not reported: Retention of sodium, chloride, water, potassium, calcium and inorganic phosphates, increased serum cholesterol, hypercalcemia^[Ref]

Dermatologic

Frequency not reported: Male pattern baldness, acne^[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting^[Ref]

Musculoskeletal

Frequency not reported: acceleration of bone maturation without producing compensatory gain in linear growth resulting in compromised adult stature^[Ref]

Hematologic

Frequency not reported: Suppression of clotting factors II, V, VII, and X; bleeding (in patients on concomitant anticoagulant therapy and polycythemia)^[Ref]

Hypersensitivity

Very rare (less than 0.01%): Anaphylactoid reactions^[Ref]

Nervous system

Frequency not reported: Headache, generalized paresthesia^[Ref]

Oncologic

Rare (less than 0.1%): Hepatocellular neoplasms^[Ref]

Respiratory

Postmarketing reports: venous thromboembolic events, including pulmonary embolism^[Ref]

Psychiatric

Frequency not reported: Steroid abuse, anxiety, depression