Zaire ebolavirus infection is a severe, acute, and often fatal viral illness first discovered in Africa in 1976. Zaire ebolavirus is one of six species of ebolavirus, and is the cause of many of the outbreaks of ebola in Africa.

Ebolavirus infection is characterized by fever, fatigue, muscle pain, headache and sore throat, followed by vomiting, diarrhea, rash, impaired kidney and liver function, and in some cases, both internal and external bleeding.

Zaire ebolavirus infection can be transmitted through contact with body fluids from an infected human or animal (bat or nonhuman primate).

Ervebo (Ebola Zaire Vaccine, Live) is FDA-approved for the prevention of disease caused by Zaire ebolavirus in individuals 18 years of age and older. The duration of protection conferred by Ervebo is unknown.

Drugs used to treat Ebola Zaire Disease Prophylaxis