Other names: HIDS; Hyperimmunoglobulin D Periodic Fever Syndrome; Mevalonate Kinase Deficiency; MKD

Hyperimmunoglobulin D Syndrome (HIDS) is one of the Major Periodic Fever Syndromes which are autoinflammatory diseases. It is a rare, autosomal recessive genetic disorder that usually presents in the first year of life. Symptoms include recurring episodes of fever, lymphadenopathy, abdominal pains, diarrhea, skin lesions and joint pain. These symptoms occur without infection being present. Blood tests of immunoglobulin levels show elevated levels of IgD and frequently levels IgA are also increased.

Drugs used to treat Hyperimmunoglobulin D Syndrome