Other names: Depressive Disorder, Other

Major depressive disorder (MDD) with acute suicidal ideation is the most severe stage of MDD.

Major depressive disorder (MDD) is a debilitating mood disorder characterized by depressed mood, diminished interests, and impaired cognitive function.

The exact cause of major depressive disorder is unknown, but genetic and environmental factors are thought to contribute.

Symptoms and severity of MDD vary by person and may include persistent feelings of sadness, hopelessness, and difficulty concentrating or performing activities of daily living. People with severe MDD may progress to having active suicidal thoughts.

Spravato (esketamine) is the first FDA approved treatment for depressive symptoms in adults with major depressive disorder with acute suicidal ideation or behavior.

Drugs used to treat Major Depressive Disorder with Acute Suicidal Ideation