Non-radiographic axial spondyloarthritis (nr-axSpA) is a chronic inflammatory condition characterized by inflammation of the spine and sacroiliac joints, which connect the lower spine and pelvis. Non-radiographic means that no damage is visible on an x-ray.
The exact cause of nr-AxSpA is not clear, though genetic factors may be involved. People with a gene called HLA-B27 are thought to have an increased risk.
Symptoms of nr-axSpA include inflammatory back pain, prolonged and severe stiffness, fatigue, and sleep disturbances resulting in reduced physical function, decreased quality of life, impaired work and home productivity and social participation.
Treatments for nr-axSpA include nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, disease-modifying antirheumatic drugs (DMARDs), corticosteroids, and biologics.
Drugs used to treat Non-Radiographic Axial Spondyloarthritis
| Name | Drug Class |
|---|---|
| Ixekizumab | Interleukin inhibitors |
| Upadacitinib | Antirheumatics |
| Secukinumab | Interleukin inhibitors |
| Taltz | Interleukin inhibitors |
| Rinvoq | Antirheumatics |
| Cosentyx | Interleukin inhibitors |
