Applies to aclidinium / formoterol: inhalation aerosol powder.
Serious side effects
Along with its needed effects, aclidinium/formoterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking aclidinium / formoterol:
More common
- Body aches or pain
- chills
- cough
- difficulty in breathing
- ear congestion
- fever
- headache
- loss of voice
- runny or stuffy nose
- sneezing
- sore throat
- unusual tiredness or weakness
Less common
- Bladder pain
- bloody or cloudy urine
- diarrhea
- difficult, burning, or painful urination
- frequent urge to urinate
- general feeling of discomfort or illness
- joint pain
- loss of appetite
- lower back or side pain
- muscle aches and pains
- nausea
- pain or tenderness around the eyes and cheekbones
- shivering
- sweating
- tightness of the chest
- trouble sleeping
- vomiting
Get emergency help immediately if any of the following symptoms of overdose occur while taking aclidinium / formoterol:
Symptoms of overdose
- Blurred vision
- dizziness
- fast, pounding, or irregular heartbeat or pulse
- headache
- muscle spasms
- nervousness
- pounding in the ears
- slow heartbeat
- tremor
Other side effects
Some side effects of aclidinium / formoterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Back, arm, or leg pain
- bone pain
- difficulty in moving
- dry mouth
- mouth or throat pain
- muscle stiffness
- toothache
For Healthcare Professionals
Applies to aclidinium / formoterol: inhalation powder.
Cardiovascular
Uncommon (0.1% to 1%): Tachycardia, electrocardiogram QTc prolonged, palpitations, blood pressure increased[Ref]
Dermatologic
Uncommon (0.1% to 1%): Rash, pruritus[Ref]
Gastrointestinal
Common (1% to 10%): Diarrhea, nausea, dry mouth, tooth abscess[Ref]
Genitourinary
Uncommon (0.1% to 1%): Urinary retention, urinary tract infection[Ref]
Hypersensitivity
Rare (less than 0.1%): Hypersensitivity
Frequency not reported: Angioedema[Ref]
Metabolic
Uncommon (0.1% to 1%): Hyperglycaemia, hypokalemia[Ref]
Musculoskeletal
Common (1% to 10%): Myalgia, muscle spasms, blood creatinine phosphokinase increased[Ref]
Nervous system
Common (1% to 10%): Headache, dizziness, tremor
Uncommon (0.1% to 1%): Dysgeusia[Ref]
Ocular
Uncommon (0.1% to 1%): Blurred vision[Ref]
Other
Common (1% to 10%): Edema peripheral[Ref]
Psychiatric
Common (1% to 10%): Anxiety, insomnia
Uncommon (0.1% to 1%): Agitation[Ref]
Respiratory
Common (1% to 10%): Cough, nasopharyngitis, sinusitis
Uncommon (0.1% to 1%): Dysphonia, throat irritation
Rare (less than 0.1%): Bronchospasm, including paradoxical[Ref]
