By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > H. pylori eradication agents > Amoxicillin and vonoprazan > Amoxicillin and vonoprazan Side Effects
H. pylori eradication agents

Amoxicillin / vonoprazan Side Effects

Applies to amoxicillin / vonoprazan: oral capsule, oral tablet.

Serious side effects

Along with its needed effects, amoxicillin/vonoprazan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amoxicillin / vonoprazan:

More common

  • Diarrhea

Less common

  • Acid or sour stomach
  • anxiety
  • belching
  • black, tarry stools
  • bladder pain
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloated
  • bloody or cloudy urine
  • blurred vision
  • body aches or pain
  • change in taste
  • chest pain or tightness
  • chills
  • cold flu-like symptoms
  • constipation
  • cracked, dry, or scaly skin
  • cough or hoarseness
  • diarrhea
  • difficult, burning, or painful urination
  • discouragement
  • dizziness
  • dry mouth
  • ear congestion
  • excess air or gas in stomach or intestines
  • eye pain
  • fainting
  • feeling sad or empty
  • fever
  • frequent urge to urinate
  • full feeling
  • general feeling of illness
  • greatly decreased frequency of urination or amount of urine
  • headache
  • heartburn
  • indigestion
  • irregular heartbeat recurrent
  • irritability
  • itching of the vagina or genitals
  • lack of appetite
  • loss of interest or pleasure
  • loss of taste
  • loss of voice
  • lower back or side pain
  • nausea
  • nervousness
  • pain or swelling in the arms or legs without any injury
  • pale skin
  • passing gas
  • pounding in the ears
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • stomach bloating, burning, cramping, discomfort, upset, or pain
  • stuffy or runny nose
  • swelling around the eyes
  • swelling of feet or lower legs
  • swelling or inflammation of the mouth
  • thick, white vaginal discharge with mild or no odor
  • trouble breathing
  • trouble concentrating
  • trouble sleeping
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • weight loss
  • white or brownish vaginal discharge

Incidence not known

  • Black, hairy tongue
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • confusion about identity, place, and time
  • coughing up blood
  • dark urine
  • diarrhea, watery and severe, which may also be bloody
  • difficulty swallowing
  • feeling of unreality
  • increased menstrual flow or vaginal bleeding
  • increased thirst
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • nosebleeds
  • palpitations
  • paralysis
  • pinpoint red spots on skin
  • prolonged bleeding from cuts
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red irritated eyes
  • red skin lesions, often with a purple center
  • seizures
  • sense of detachment from self or body
  • stiff neck or back
  • swollen glands
  • unpleasant breath odor
  • vomiting of blood
  • yellow eyes or skin

For Healthcare Professionals

Applies to amoxicillin / vonoprazan: oral kit.

General

The most common adverse reaction leading to discontinuation of this product was rash.[Ref]

Cardiovascular

Common (1% to 10%): Hypertension (includes increased blood pressure)

Frequency not reported: QT prolongation, tachycardia[Ref]

Dermatologic

Frequency not reported: Dermatitis, dry skin, rash

Amoxicillin and Vonoprazan:

-Frequency not reported: Severe cutaneous adverse reactions (including Stevens-Johnson syndrome, toxic epidermal necrolysis)

Amoxicillin:

-Frequency not reported: Erythematous skin rash

-Postmarketing reports: Mucocutaneous candidiasis, erythematous maculopapular rashes, erythema multiforme, exfoliative dermatitis, urticaria, toxic epidermal necrolysis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis

Vonoprazan:

-Postmarketing reports: Urticaria, drug eruption, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, abdominal pain (includes abdominal discomfort, abdominal pain, lower abdominal pain, upper abdominal pain)

Frequency not reported: Abdominal distension, constipation, dry mouth, duodenal polyp, duodenal ulcer, dyspepsia, flatulence, gastric ulcer, gastroesophageal reflux disease, hematochezia, large intestine polyp, nausea, rectal polyp, stomatitis, tongue discomfort, vomiting, anal fungal infection, gastrointestinal viral infection, oral fungal infection, tongue fungal infection

Amoxicillin:

-Frequency not reported: Clostridioides difficile-associated diarrhea

-Postmarketing reports: Black hairy tongue, hemorrhagic/pseudomembranous colitis, tooth discoloration (brown, yellow, or gray staining)

Acid-Suppressing Therapies:

-Frequency not reported: C difficile-associated diarrhea[Ref]

Onset of pseudomembranous colitis symptoms has been reported during or after antibacterial treatment.

Most reports of tooth discoloration with amoxicillin occurred in pediatric patients; discoloration was reduced/eliminated with brushing or dental cleaning in most cases.[Ref]

Genitourinary

Common (1% to 10%): Vulvovaginal candidiasis (includes urogenital fungal infection, vulvovaginal candidiasis, vulvovaginal mycotic infection, vulvovaginal pruritus, genital pruritus, genital fungal infection)

Frequency not reported: Urinary tract infection, vaginal discharge

Amoxicillin:

-Postmarketing reports: Crystalluria[Ref]

Hematologic

Hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, and agranulocytosis have been reported during therapy with penicillins; these reactions were usually reversible when therapy was stopped and were believed to be hypersensitivity phenomena.[Ref]

Frequency not reported: Anemia, leukocytosis, leukopenia, neutropenia

Penicillins:

-Postmarketing reports: Hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, agranulocytosis[Ref]

Hepatic

Frequency not reported: Abnormal liver function test

Vonoprazan:

-Postmarketing reports: Hepatic injury, hepatic failure, jaundice[Ref]

Hypersensitivity

Frequency not reported: Drug hypersensitivity

Amoxicillin and Vonoprazan:

-Frequency not reported: Hypersensitivity reactions (e.g., anaphylaxis, anaphylactic shock, rash, erythema multiforme, Henoch-Schonlein purpura)

Amoxicillin:

-Postmarketing reports: Anaphylaxis, serum sickness-like reactions, hypersensitivity vasculitis

Vonoprazan:

-Postmarketing reports: Anaphylactic shock[Ref]

Metabolic

Frequency not reported: Decreased appetite[Ref]

Musculoskeletal

Frequency not reported: Bone fracture[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dysgeusia (includes taste disorder)

Frequency not reported: Ageusia, dizziness, tension headache

Amoxicillin:

-Postmarketing reports: Reversible hyperactivity, convulsions, aseptic meningitis[Ref]

Ocular

Frequency not reported: Orbital edema[Ref]

Other

Frequency not reported: Fatigue, pyrexia, viral infection[Ref]

Psychiatric

Frequency not reported: Anxiety, depression, insomnia

Amoxicillin:

-Postmarketing reports: Agitation, confusion, behavioral changes[Ref]

Renal

Frequency not reported: Renal hypertrophy, tubulointerstitial nephritis[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis

Frequency not reported: Pneumonia, upper respiratory tract infection, cough, nasal polyps, oropharyngeal pain[Ref]

Share this Article
Latest News
Medical News

Obesity, unhealthy lifestyles may cause heart to age by 5–45 years

May 08, 2025
Aging: As little as 5 minutes of exercise may keep the brain healthy
Prostate cancer: Simple urine test may help with early detection
Cancer treatment side effects: Exercise may reduce pain, fatigue
Alzheimer's: Exercising in middle age may reduce beta-amyloid in brain...
Heart disease: Just 3 minutes of 'incidental activity' may lower...
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by