Applies to benzoyl peroxide/tretinoin topical: topical application cream.
Serious side effects
Along with its needed effects, benzoyl peroxide/tretinoin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking benzoyl peroxide / tretinoin topical:
More common
- Pain, burning, changes in color, dryness, itching, peeling, redness, scaling, stinging, or swelling of the skin where the medicine is applied
Incidence not known
- Chest tightness
- cough
- difficulty swallowing
- dizziness
- fast heartbeat
- hives, itching, or skin rash
- increased sensitivity of the skin to sunlight
- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- redness or other discoloration of the skin
- severe sunburn
- trouble breathing
- unusual tiredness or weakness
For Healthcare Professionals
Applies to benzoyl peroxide / tretinoin topical: topical cream.
Immunologic
Postmarketing reports: Anaphylaxis, angioedema, and urticaria[Ref]
Dermatologic
Very common (10% or more): Application site pain (10.6%)
Common (1% to 10%): Application Site Dryness, application site exfoliation, application site erythema, application site dermatitis, application site pruritus, application site irritation[Ref]
