Applies to beractant: intratracheal suspension.

Side effects include:

Transient bradycardia, oxygen desaturation, endotracheal tube reflux, pallor, vasoconstriction, hypotension, endotracheal tube blockage, hypertension, hypocarbia, hypercarbia, apnea.

For Healthcare Professionals

Applies to beractant: intratracheal suspension.

General

The most commonly reported adverse experiences were associated with the dosing procedure; transient bradycardia occurred with 11.9% of doses and oxygen desaturation occurred with 9.8% of doses.^[Ref]

Cardiovascular

Very common (10% or more): Transient bradycardia (11.9%)

Uncommon (0.1% to 1%): Pallor, vasoconstriction, hypotension, hypertension, hypercarbia, hypocarbia

Frequency not reported: Tachycardia, ventricular tachycardia, aortic thrombosis, cardiac failure, cardio-respiratory arrest, increased apical pulse, persistent fetal circulation, air embolism, total anomalous pulmonary venous return^[Ref]

Respiratory

Common (1% to 10%): Oxygen desaturation

Uncommon (0.1% to 1%): Apnea

Frequency not reported: Lung consolidation, blood from the endotracheal tube, deterioration after weaning, respiratory decompensation, subglottic stenosis, paralyzed diaphragm, respiratory failure^[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Endotracheal tube reflux, endotracheal tube blockage

Frequency not reported: Abdominal distension, hemorrhage, intestinal perforations, volvulus, bowel infarct, feeding intolerance, stress ulcer^[Ref]

Endocrine

Frequency not reported: Adrenal hemorrhage, inappropriate ADH secretion, hyperphosphatemia^[Ref]

Hematologic

Frequency not reported: Coagulopathy, thrombocytopenia, disseminated intravascular coagulation^[Ref]

Hepatic

Frequency not reported: Hepatic failure^[Ref]

Musculoskeletal

Frequency not reported: Inguinal hernia^[Ref]

Nervous system

Frequency not reported: Seizures^[Ref]

Renal

Frequency not reported: Renal failure, hematuria^[Ref]