Summary of Use during Lactation

Because no information is available on the use of edoxaban during breastfeeding and the drug is orally absorbable, an alternate drug is preferred while nursing a newborn or preterm infant.[1][2][3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acenocoumarol, Dalteparin, Enoxaparin, Heparin, Warfarin

References

1.

Bates SM, Greer IA, Middeldorp S et al. VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141 (2 Suppl):e691S-736S. [PMC free article: PMC3278054] [PubMed: 22315276]

2.

Vanassche T, Vandenbriele C, Peerlinck K, Verhamme P. Pharmacotherapy with oral Xa inhibitors for venous thromboembolism. Expert Opin Pharmacother. 2015;16:645-58. [PubMed: 25554350]

3.

Cohen H, Arachchillage DR, Beyer-Westendorf J et al. Direct oral anticoagulants and women. Semin Thromb Hemost. 2016;42:789-97. [PubMed: 27706531]

Substance Name

Edoxaban

CAS Registry Number

480449-70-5

Drug Class

• Breast Feeding
• Lactation
• Anticoagulants
• Antithrombins