Summary of Use during Lactation

No information is available on the clinical use of inclisiran during breastfeeding. Because inclisiran is a large oligonucleotide, the amount in milk is likely to be very low and absorption by the infant is probably minimal. If inclisiran is required by the mother, it is not a reason to discontinue breastfeeding. Until more data become available, inclisiran should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Cholestyramine, Colesevelam, Colestipol

Substance Name

Inclisiran

CAS Registry Number

1639324-58-5

Drug Class

Breast Feeding

Lactation

Milk, Human

Anticholesteremic Agents

Antilipemic Agents