Summary of Use during Lactation

No information is available on the clinical use of zanubrutinib during breastfeeding. Because zanubrutinib is 94% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during zanubrutinib therapy and for at least 2 weeks after the last dose.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Name

Zanubrutinib

CAS Registry Number

1691249-45-2

Drug Class

Breast Feeding

Lactation

Antineoplastic Agents

Enzyme Inhibitors

Hematologic Agents

Protein Kinase Inhibitors