Note: This document contains side effect information about calcipotriene topical. Some dosage forms listed on this page may not apply to the brand name Calcitrene.
Summary
Common side effects of Calcitrene include: skin irritation. Continue reading for a comprehensive list of adverse effects.
Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution.
Serious side effects of Calcitrene
Along with its needed effects, calcipotriene topical (the active ingredient contained in Calcitrene) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking calcipotriene topical:
More common
- Skin redness, swelling, or itching
- skin rash
- worsening of psoriasis
Get emergency help immediately if any of the following symptoms of overdose occur while taking calcipotriene topical:
Symptoms of overdose
- Confusion
- constipation
- discouragement
- dry mouth
- feeling sad or empty
- headache
- incoherent speech
- increased urination
- irritability
- lack of appetite
- loss of interest or pleasure
- metallic taste
- muscle weakness
- nausea
- stomach pain
- thirst
- tiredness
- trouble concentrating
- trouble sleeping
- unusual tiredness
- vomiting
- weight loss
Other side effects of Calcitrene
Some side effects of calcipotriene topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Burning, dryness, irritation, peeling, or redness of the skin
Less common
- Pain at the application site
Rare
- Darker color in the treated areas of the skin
- pus in the hair follicles
For Healthcare Professionals
Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution.
General
The most commonly reported side effects were burning, stinging, tingling, and skin irritation.[Ref]
Hypersensitivity
Very rare (less than 0.01%): Allergic reactions (including angioedema)[Ref]
Dermatologic
Very common (10% or more): Transient burning (about 23%), stinging (about 23%), tingling (about 23%), skin irritation (up to 15%), rash (11%)
Common (1% to 10%): Pruritus, dermatitis, contact dermatitis (including facial and perioral), dry skin, irritation, worsening of psoriasis, erythema, peeling
Uncommon (0.1% to 1%): Skin atrophy, hyperpigmentation, folliculitis, eczema
Frequency not reported: Transient changes in skin pigmentation, transient photosensitivity, urticaria, angioedema, skin exfoliation[Ref]
Metabolic
Uncommon (0.1% to 1%): Hypercalcemia
Rare (less than 0.1%): Transient increases in serum calcium
Very rare (less than 0.01%): Hypercalcemia, hypercalciuria (especially if the total recommended dose is exceeded)[Ref]
Local
Very common (10% or more): Lesional/perilesional irritation (up to 39%), face and/or scalp irritation (up to 25%)[Ref]
Other
Frequency not reported: Periorbital or face edema[Ref]
