Drug Class: Upper respiratory combinations
Usual Adult Dose for Cold Symptoms
Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours
Usual Adult Dose for Influenza
Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours
Usual Pediatric Dose for Cold Symptoms
Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours
6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours
Usual Pediatric Dose for Influenza
Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours
6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Use with caution.
Precautions
CONTRAINDICATIONS:
- Current use of any other drug containing paracetamol.
- Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
- Current use of any other drug containing diphenhydramine, including topical preparations.
Safety and efficacy have not been established in patients younger than 6 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available