Drug Class: Antacids
Usual Adult Dose for Dyspepsia
Oral suspensions:
Aluminum hydroxide 400 mg-magnesium hydroxide 400 mg-simethicone 40 mg/10 mL: 10 to 20 mL orally 4 times a day or as directed
- Maximum dose: 80 mL/day
Aluminum hydroxide 800 mg-magnesium hydroxide 800 mg-simethicone 80 mg/10 mL: 10 to 20 mL orally between meals, at bedtime, or as directed
- Maximum dose: 60 mL/day
Tablets:
Aluminum hydroxide 200 mg-magnesium hydroxide 200 mg-simethicone 25 mg: 2 to 4 tablets orally up to every hour as needed for symptoms, or as directed
- Maximum dose: 12 tablets/day
Duration of therapy: 2 weeks
Comments:
- Tablets should be chewed prior to swallowing.
- Doses should be measured with the included measuring cup.
Uses:
- Relief of acid indigestion
- Relief of bloating, discomfort, and pressure associated with gas
- Relief of heartburn
- Relief of sour stomach
- Relief of upset stomach due to acid indigestion, heartburn, and/or sour stomach
Usual Adult Dose for Flatulence
Oral suspensions:
Aluminum hydroxide 400 mg-magnesium hydroxide 400 mg-simethicone 40 mg/10 mL: 10 to 20 mL orally 4 times a day or as directed
- Maximum dose: 80 mL/day
Aluminum hydroxide 800 mg-magnesium hydroxide 800 mg-simethicone 80 mg/10 mL: 10 to 20 mL orally between meals, at bedtime, or as directed
- Maximum dose: 60 mL/day
Tablets:
Aluminum hydroxide 200 mg-magnesium hydroxide 200 mg-simethicone 25 mg: 2 to 4 tablets orally up to every hour as needed for symptoms, or as directed
- Maximum dose: 12 tablets/day
Duration of therapy: 2 weeks
Comments:
- Tablets should be chewed prior to swallowing.
- Doses should be measured with the included measuring cup.
Uses:
- Relief of acid indigestion
- Relief of bloating, discomfort, and pressure associated with gas
- Relief of heartburn
- Relief of sour stomach
- Relief of upset stomach due to acid indigestion, heartburn, and/or sour stomach
Usual Pediatric Dose for Dyspepsia
12 years and over:
Oral suspensions:
Aluminum hydroxide 400 mg-magnesium hydroxide 400 mg-simethicone 40 mg/10 mL: 10 to 20 mL orally 4 times a day or as directed
- Maximum dose: 80 mL/day
Aluminum hydroxide 800 mg-magnesium hydroxide 800 mg-simethicone 80 mg/10 mL: 10 to 20 mL orally between meals, at bedtime, or as directed
- Maximum dose: 60 mL/day
Tablets:
Aluminum hydroxide 200 mg-magnesium hydroxide 200 mg-simethicone 25 mg: 2 to 4 tablets orally up to every hour as needed for symptoms, or as directed
- Maximum dose: 12 tablets/day
Duration of therapy: 2 weeks
Comments:
- Tablets should be chewed prior to swallowing.
- Doses should be measured with the included measuring cup.
Uses:
- Relief of acid indigestion
- Relief of bloating, discomfort, and pressure associated with gas
- Relief of heartburn
- Relief of sour stomach
- Relief of upset stomach due to acid indigestion, heartburn, and/or sour stomach
Usual Pediatric Dose for Flatulence
12 years and over:
Oral suspensions:
Aluminum hydroxide 400 mg-magnesium hydroxide 400 mg-simethicone 40 mg/10 mL: 10 to 20 mL orally 4 times a day or as directed
- Maximum dose: 80 mL/day
Aluminum hydroxide 800 mg-magnesium hydroxide 800 mg-simethicone 80 mg/10 mL: 10 to 20 mL orally between meals, at bedtime, or as directed
- Maximum dose: 60 mL/day
Tablets:
Aluminum hydroxide 200 mg-magnesium hydroxide 200 mg-simethicone 25 mg: 2 to 4 tablets orally up to every hour as needed for symptoms, or as directed
- Maximum dose: 12 tablets/day
Duration of therapy: 2 weeks
Comments:
- Tablets should be chewed prior to swallowing.
- Doses should be measured with the included measuring cup.
Uses:
- Relief of acid indigestion
- Relief of bloating, discomfort, and pressure associated with gas
- Relief of heartburn
- Relief of sour stomach
- Relief of upset stomach due to acid indigestion, heartburn, and/or sour stomach
Renal Dose Adjustments
Use with caution.
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS: None.
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Oral liquid: Shake well prior to use.
Storage requirements:
- Oral suspension: Do not freeze
General:
- Some oral suspensions do not meet United States Pharmacopeia (USP) requirements for preservative effectiveness.
Patient advice:
- Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
- Patients should be instructed to avoid using products if the tamper evident feature(s) are torn, broken, and/or missing.
