Inhaled corticosteroids
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Asmanex Dosage

Drug Detail:Asmanex twisthaler (Mometasone inhalation [ moe-met-a-sone ])

Generic Name: Mometasone Furoate 220ug

Dosage Form: inhalant

Drug Class: Inhaled corticosteroids

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

​Administration Information

​Administer ASMANEX TWISTHALER by the orally inhaled route only. Instruct patients to inhale rapidly and deeply. After administration, advise patients to rinse the mouth with water and spit out contents without swallowing. Individual patients will experience a variable time to onset and degree of symptom relief. Maximum benefit may not be achieved for 1 to 2 weeks or longer after initiation of treatment. After asthma stability has been achieved, it is desirable to titrate to the lowest effective dosage to reduce the possibility of side effects. For patients ≥12 years of age who do not respond adequately to the starting dose after 2 weeks of therapy, higher doses may provide additional asthma control. The safety and efficacy of ASMANEX TWISTHALER when administered in excess of recommended doses have not been established.

Recommended Dosages in Adult and Pediatric Patients 4 Years of Age and Older

The recommended starting doses and highest recommended daily dose for ASMANEX TWISTHALER treatment based on prior asthma therapy are provided in Table 1.

Table 1: Recommended Dosages for ASMANEX TWISTHALER Treatment
Previous Therapy Recommended Starting Dose Highest Recommended Daily Dose
*
When administered once daily, ASMANEX TWISTHALER should be taken only in the evening.
†
The 440 mcg daily dose may be administered in divided doses of 220 mcg twice daily or as 440 mcg once daily.
‡
For Patients Currently Receiving Chronic Oral Corticosteroid Therapy: Prednisone should be reduced no faster than 2.5 mg/day on a weekly basis, beginning after at least 1 week of ASMANEX TWISTHALER therapy. Monitor patients carefully for signs of asthma instability, including serial objective measures of airflow, and for signs of adrenal insufficiency during steroid taper and following discontinuation of oral corticosteroid therapy [see Warnings and Precautions (5.5)].
§
Recommended pediatric dosage is 110 mcg once daily in the evening regardless of prior therapy.
Patients ≥12 years who received bronchodilators alone 220 mcg once daily in the evening* 440 mcg†
Patients ≥12 years who received inhaled corticosteroids 220 mcg once daily in the evening* 440 mcg†
Patients ≥12 years who received oral corticosteroids‡ 440 mcg twice daily 880 mcg
Children 4-11 years of age§ 110 mcg once daily in the evening* 110 mcg*
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