Usual Adult Dose for Bacterial Conjunctivitis

Ointment:

• Days 1 and 2: Apply a one-half inch ribbon into the conjunctival sac of the affected eye(s) 3 times a day.
• Days 3 through 7: Apply a one-half inch ribbon into the conjunctival sac of the affected eye(s) 2 times a day.

Solution:

• Days 1 and 2: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) every 2 hours while awake.
• Days 3 through 7: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) every 4 hours while awake.

Use: For the treatment of bacterial conjunctivitis due to susceptible strains of:

• Ointment: Staphylococcus aureus, S epidermidis, Streptococcus pneumoniae, Streptococcus (viridans group), Haemophilus influenzae
• Solution: H influenzae, S aureus, S epidermidis, S pneumoniae

Usual Adult Dose for Corneal Ulcers

Solution:

• Day 1: Instill 2 drops into the affected eye(s) every 15 minutes for the first 6 hours and then 2 drops into the affected eye(s) every 30 minutes for the remainder of the day.
• Day 2: Instill 2 drops into the affected eye(s) every hour.
• Days 3 through 14: Instill 2 drops into the affected eye(s) every 4 hours.

Comments: May continue treatment after 14 days if corneal reepithelialization has not occurred

Use: For the treatment of corneal ulcers due to susceptible strains of Pseudomonas aeruginosa, Serratia marcescens, S aureus, S epidermidis, S pneumoniae, Streptococcus (viridans group)

Usual Pediatric Dose for Bacterial Conjunctivitis

Ointment:
2 years or older:

• Days 1 and 2: Apply a one-half inch ribbon into the conjunctival sac of the affected eye(s) 3 times a day.
• Days 3 through 7: Apply a one-half inch ribbon into the conjunctival sac of the affected eye(s) 2 times a day.

Solution:
1 year or older:

• Days 1 and 2: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) every 2 hours while awake.
• Days 3 through 7: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) every 4 hours while awake.

Use: For the treatment of bacterial conjunctivitis due to susceptible strains of:

• Ointment: S aureus, S epidermidis, S pneumoniae, Streptococcus (viridans group), H influenzae
• Solution: H influenzae, S aureus, S epidermidis, S pneumoniae

Usual Pediatric Dose for Corneal Ulcers

Solution:
2 years or older:

• Day 1: Instill 2 drops into the affected eye(s) every 15 minutes for the first 6 hours and then 2 drops into the affected eye(s) every 30 minutes for the remainder of the day.
• Day 2: Instill 2 drops into the affected eye(s) every hour.
• Days 3 through 14: Instill 2 drops into the affected eye(s) every 4 hours.

Comments: May continue treatment after 14 days if corneal reepithelialization has not occurred

Use: For the treatment of corneal ulcers due to susceptible strains of P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, Streptococcus (viridans group)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 2 years (ointment) or 1 year (solution).

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For topical ophthalmic use only (not for injection into the eye)

Storage requirements:

• Store at 2C to 25C (36F to 77F).
• Solution: Protect from light.

Patient advice:

• Do not wear contact lenses if you have signs/symptoms of bacterial conjunctivitis or during therapy.
• Avoid contaminating the applicator tip with material from the eye, fingers, or any other source; do not touch the applicator tip to any surface.
• Stop this drug at first sign of skin rash or any other sign of hypersensitivity.