Drug Detail:Clobetasol (Clobetasol topical [ kloe-bay-ta-sol ])
Drug Class: Topical steroids
Usual Adult Dose for Dermatitis
- Solution, spray, ointment, gel, foam, lotion, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely.
- Shampoo: Apply to dry scalp once a day in a thin film to the affected areas only and leave in place for 15 minutes before lathering and rinsing.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fluid ounce) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Relief of corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Adult Dose for Eczema
- Solution, spray, ointment, gel, foam, lotion, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely.
- Shampoo: Apply to dry scalp once a day in a thin film to the affected areas only and leave in place for 15 minutes before lathering and rinsing.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fluid ounce) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Relief of corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Adult Dose for Psoriasis
- Solution, spray, ointment, gel, foam, lotion, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely.
- Shampoo: Apply to dry scalp once a day in a thin film to the affected areas only and leave in place for 15 minutes before lathering and rinsing.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fluid ounce) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Relief of corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Adult Dose for Dermatological Disorders
- Solution, spray, ointment, gel, foam, lotion, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely.
- Shampoo: Apply to dry scalp once a day in a thin film to the affected areas only and leave in place for 15 minutes before lathering and rinsing.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fluid ounce) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Relief of corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Adult Dose for Lichen Planus
- Solution, spray, ointment, gel, foam, lotion, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely.
- Shampoo: Apply to dry scalp once a day in a thin film to the affected areas only and leave in place for 15 minutes before lathering and rinsing.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fluid ounce) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Relief of corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Pediatric Dose for Dermatitis
- Solution, ointment, gel, foam, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely. Not recommended for use in children under 12 years of age.
- Shampoo, spray, and lotion formulations: Not recommended for use in children under 18 years of age.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Pediatric Dose for Eczema
- Solution, ointment, gel, foam, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely. Not recommended for use in children under 12 years of age.
- Shampoo, spray, and lotion formulations: Not recommended for use in children under 18 years of age.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Pediatric Dose for Psoriasis
- Solution, ointment, gel, foam, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely. Not recommended for use in children under 12 years of age.
- Shampoo, spray, and lotion formulations: Not recommended for use in children under 18 years of age.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Pediatric Dose for Dermatological Disorders
- Solution, ointment, gel, foam, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely. Not recommended for use in children under 12 years of age.
- Shampoo, spray, and lotion formulations: Not recommended for use in children under 18 years of age.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Usual Pediatric Dose for Lichen Planus
- Solution, ointment, gel, foam, cream formulations: Apply a thin layer to affected areas twice a day and rub in gently and completely. Not recommended for use in children under 12 years of age.
- Shampoo, spray, and lotion formulations: Not recommended for use in children under 18 years of age.
Maximum dose: The total dosage should not exceed 50 g (50 mL or 1.75 fl. oz.) per week.
Duration of therapy: Treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that
have not improved after the initial 2 weeks of treatment.
Comments: Unless directed by a healthcare professional, this drug should not be used with occlusive dressings.
Uses:
- Corticosteroid-responsive inflammatory and pruritic dermatoses; psoriasis; recalcitrant eczemas, lichen planus, discoid lupus erythematosus, and other conditions which do not respond satisfactorily to less active steroids.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to any of the ingredients
- If treatment is required for use in children, it is recommended that it should be reviewed weekly.
Safety and efficacy have not been established in patients younger than 18 years and its use in pediatric patients under 12 years of age is not recommended.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Do not use on your face, groin, armpits, lips, or in your eyes.
- Do not cover your head with a shower cap or bathing cap.
- Wash your hands after applying the drug unless it is the hands that are being treated.
- If drug enters the eye, the affected eye should be rinsed immediately with plenty of water.
Frequently asked questions
- Does clobetasol cause hair loss or growth?
- How do you apply clobetasol propionate for lichen sclerosus?
- What is clobetasol propionate cream used for?
- How effective is it for hair growth?
- How long does it take to work?
- How do you use clobetasol propionate on your scalp?
- Can you use clobetasol on your face?
- Clobetasol vs. triamcinolone - how do they compare?
- What causes Plaque Psoriasis?
- Halobetasol vs. clobetasol - how do they compare?
- Can clobetasol be used for toenail fungus?
- Can this drug make you gain weight?
- Can clobetasol propionate be used for poison ivy?
- How long does clobetasol stay in your system?
- How long should you use clobetasol propionate cream for?