Drug Detail:Desloratadine (Desloratadine [ des-lor-a-ta-deen ])
Drug Class: Antihistamines
Usual Adult Dose for Allergic Rhinitis
5 mg orally once a day
Uses:
- Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis
- Relief of nasal and non-nasal symptoms of perennial allergic rhinitis
- Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria
Usual Adult Dose for Urticaria
5 mg orally once a day
Uses:
- Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis
- Relief of nasal and non-nasal symptoms of perennial allergic rhinitis
- Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria
Usual Pediatric Dose for Allergic Rhinitis
6 to 11 months: 1 mg orally once a day
12 months to 5 years: 1.25 mg orally once a day
6 to 11 years: 2.5 mg orally once a day
12 years and older: 5 mg orally once a day
Uses:
- Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis
- Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria
- Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis
Usual Pediatric Dose for Urticaria
6 to 11 months: 1 mg orally once a day
12 months to 5 years: 1.25 mg orally once a day
6 to 11 years: 2.5 mg orally once a day
12 years and older: 5 mg orally once a day
Uses:
- Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis
- Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria
- Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis
Renal Dose Adjustments
Renal dysfunction:
Children: Data not available
Adults:
- Initial dose: 5 mg orally every other day
Liver Dose Adjustments
Liver dysfunction:
Children: Data not available
Adults:
- Initial dose: 5 mg orally every other day
Dose Adjustments
Hypersensitivity reaction: This drug should be stopped, and an alternative treatment should be considered.
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to the active component, loratadine, or any of the ingredients
Safety and efficacy have not been established in patients younger than 6 months.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Take without regard to food.
- Tablets should be swallowed with fluid (e.g., a glass of water).
- Oral disintegrating tablets should remove from the packaging immediately prior to administration; the tablet should be allowed to disintegrate on the tongue before swallowing.
- Oral solutions/syrups should be measured with the included oral dropper/syringe.
Storage requirements:
- Oral solution: Do not freeze
- Tablets: Protect from moisture
Patient advice:
- Inform patients that this drug may cause drowsiness, and they should avoid driving or operating machinery if these side effects occur.
- Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
