Drug Detail:Dynapen (Dicloxacillin [ dye-klox-a-sil-in ])
Drug Class: Penicillinase resistant penicillins
Usual Adult Dose for Bronchitis
250 to 500 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.
Usual Adult Dose for Pharyngitis
250 mg orally every 6 hours for 10 days, depending on the nature and severity of the infection.
Usual Adult Dose for Pneumonia
500 mg orally every 6 hours for up to 21 days, depending on the nature and severity of the infection.
Usual Adult Dose for Skin or Soft Tissue Infection
500 mg orally every 6 hours for 7 days, or for 3 days after acute inflammation resolves, depending on the nature and severity of the infection.
Usual Adult Dose for Upper Respiratory Tract Infection
250 mg orally every 6 hours for 7 to 21 days, depending on the nature and severity of the infection.
Usual Pediatric Dose for Skin or Soft Tissue Infection
<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.
>40 kg: 125 to 250 mg orally every 6 hours.
Usual Pediatric Dose for Upper Respiratory Tract Infection
<40 kg: 3.125 to 6.25 mg/kg orally every 6 hours.
>40 kg: 125 to 250 mg orally every 6 hours.
Usual Pediatric Dose for Osteomyelitis
Following initial intravenous therapy:
>= 1 year:
<40 kg: 12.5 to 25 mg/kg orally every 6 hours, not to exceed 2000 mg/24 hours.
>40 kg: 250 mg orally every 6 hours, not to exceed 2000 mg/24 hours.
Usual Pediatric Dose for Pneumonia
<40 kg: 6.25 mg/kg orally every 6 hours.
>40 kg: 250 mg orally every 6 hours.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Data not available
Precautions
Oral antibiotics are not recommended for patients with severe or life-threatening infections.
Dialysis
No adjustment recommended
Other Comments
Dicloxacillin is best absorbed when administered on an empty stomach, preferably 1 to 2 hours before meals.
