Usual Adult Dose for Irritable Bowel Syndrome

Oral:
Initial dose: 20 mg orally four times a day
Maintenance dose: Up to 40 mg orally four times a day, after one week with initial dose

Comments:

• Discontinue this drug if efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day.
• Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks.

Intramuscular:
10 to 20 mg four times a day
Duration of therapy: 1 or 2 weeks, when patient cannot take oral form

Comments: Administer injection via IM only

Uses: Treatment of patients with functional bowel/irritable bowel syndrome

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Dicyclomine is contraindicated in infants under 6 months of age.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Dicyclomine injection is for IM administration only.
• Inspect parenteral products visually for particulate matter and discoloration prior administration.
• Aspirate the syringe before injecting to avoid intravascular injection (thrombosis may occur if the drug is inadvertently injected intravascularly).

Patient advice: This drug may cause drowsiness or blurred vision; avoid activities that require mental alertness, such as operating a motor vehicle or other machinery or performing hazardous work while taking this drug.