Usual Adult Dose for Contraception

One 68 mg implant subdermally just under the skin at the inner side of the non-dominant upper arm

• Remove no later than the end of the third year

• Implant may be replaced by a new implant at the time of removal.
• If no preceding hormonal contraceptive in the last month: insert between days 1 and 5 of the menstrual cycle, even if still bleeding.
• Switching from combined hormonal contraceptive: insert the day after the last active tablet of the oral contraceptive, or the day of removal of the vaginal ring or patch.
• Switching from progestin-only injectable contraceptive: implant the day the next injection is due.
• Switching from progestin-only minipill: switch any day of the month, within 24 hours after the last tablet.
• Switching from progestin-only implant or intrauterine device: insert the same day the previous contraception is removed.
• Following first trimester abortion or miscarriage: insert within 5 days of abortion/miscarriage.
• Following second trimester abortion or miscarriage: insert between 21 and 28 days of abortion/miscarriage.
• Postpartum, not breastfeeding: insert between 21 and 28 days postpartum.
• Postpartum, breastfeeding: insert after the fourth week postpartum, advise use of a barrier contraceptive method until 7 days after implantation.
• If inserted as recommended above, back up contraception is not necessary. If deviating from the above recommendations, a barrier contraceptive is recommended until 7 days after insertion.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Contraindicated

Dialysis

Data not available

Other Comments

Administration advice:

• An implant should always be removed before inserting a new one.
• The manufacturer product information should be consulted.

• Advise patients that this product does not protect against HIV infection or other sexually transmitted diseases.