IMPEKLO lotion is for topical use only, and not for ophthalmic, oral or intravaginal use.

Avoid use of IMPEKLO lotion on the face, axillae, or groin and avoid use if there is atrophy at the treatment site.

IMPEKLO lotion should be applied to the affected skin areas twice daily and rubbed in gently and completely. Avoid contact with eyes. Wash hands after each application.

The total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Do not use more than 10 pump actuations per application twice daily or 20 pump actuations per day for more than 7 days.

IMPEKLO lotion contains a topical corticosteroid; therefore treatment should be limited to 2 consecutive weeks for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and up to 2 additional weeks in localized lesions (less than 10% body surface area) of moderate to severe plaque psoriasis that have not sufficiently improved after the initial 2 weeks of treatment. Discontinue use when control is achieved.

Unless directed by physician, IMPEKLO lotion should not be used with occlusive dressings.