Usual Adult Dose for Vaccination

Two 0.5 mL doses, intramuscularly, given 21 days apart

Usual Pediatric Dose for Vaccination

6 months to 17 years:
Two 0.25 mL doses, intramuscularly, given 21 days apart

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 6 months.

To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• The anterolateral thigh is the preferred site for infants 6 to 11 months.
• The deltoid muscle of the upper arm is the preferred site for patients 1 year and older.
• Mix thoroughly by inversion before each administration.
• If the vaccine has been refrigerated, place at room temperature for a minimum of 15 minutes prior to administration.

• Refrigerate; do not freeze
• Protect from light
• Discard if frozen

• Place antigen and adjuvant at room temperature for a minimum of 15 minutes before mixing.
• Mix thoroughly by inversion; label antigen (now containing vaccine) vial with date and time mixed.
• After mixing, store at room temperature or refrigerated for up to 24 hours.

• Do not mix with any other vaccine in the same syringe or vial.