Drug Detail:Ingrezza (Valbenazine [ val-ben-a-zeen ])
Generic Name: VALBENAZINE TOSYLATE 60mg
Dosage Form: capsule
Drug Class: VMAT2 inhibitors
Drug Detail:Ingrezza (Valbenazine [ val-ben-a-zeen ])
Generic Name: VALBENAZINE TOSYLATE 60mg
Dosage Form: capsule
Drug Class: VMAT2 inhibitors
The initial dosage for INGREZZA is 40 mg once daily. After one week, increase the dose to the recommended dosage of 80 mg once daily. A dosage of 40 mg or 60 mg once daily may be considered depending on response and tolerability.
Administer INGREZZA orally with or without food [see Clinical Pharmacology (12.3)].
The recommended dosage for patients with moderate or severe hepatic impairment (Child-Pugh score 7 to 15) is INGREZZA 40 mg once daily [see Use in Specific Populations (8.7), Clinical Pharmacology (12.3)].
The recommended dosage for known CYP2D6 poor metabolizers is INGREZZA 40 mg once daily [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)].
Coadministration with Strong CYP3A4 Inducers
Concomitant use of strong CYP3A4 inducers with INGREZZA is not recommended [see Drug Interactions (7.1)].
Coadministration with Strong CYP3A4 Inhibitors
The recommended dosage for patients receiving strong CYP3A4 inhibitors is INGREZZA 40 mg once daily [see Drug Interactions (7.1)].
Coadministration with Strong CYP2D6 Inhibitors
The recommended dosage for patients receiving strong CYP2D6 inhibitors is INGREZZA 40 mg once daily [see Drug Interactions (7.1)].