Usual Adult Dose for Corneal Refractive Surgery

0.4% Ophthalmic Solution: Instill 1 drop in the operated eye(s) four times a day as needed for pain and burning/stinging for up to 4 days following corneal refractive surgery

Use: For the relief of ocular pain and burning/stinging following corneal refractive surgery

Usual Adult Dose for Postoperative Ocular Inflammation

0.45% Ophthalmic Solution: Instill 1 drop in the affected eye(s) twice a day beginning 1 day prior to cataract surgery, continuing on the day of surgery, and through the first 2 weeks of the postoperative period

0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day beginning 24 hours after cataract surgery and continue through the first 2 weeks of the postoperative period

Use: For the treatment of pain and inflammation following cataract surgery

Usual Adult Dose for Seasonal Allergic Conjunctivitis

0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day

Use: For the temporary relief of ocular itching due to seasonal allergic conjunctivitis

Usual Pediatric Dose for Corneal Refractive Surgery

3 years or older:
0.4% Ophthalmic Solution: Instill 1 drop in the operated eye(s) four times a day as needed for pain and burning/stinging for up to 4 days following corneal refractive surgery

Use: For the relief of ocular pain and burning/stinging following corneal refractive surgery

Usual Pediatric Dose for Postoperative Ocular Inflammation

2 years or older:
0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day beginning 24 hours after cataract surgery and continue through the first 2 weeks of the postoperative period

Uses: For the treatment of pain and inflammation following cataract surgery

Usual Pediatric Dose for Seasonal Allergic Conjunctivitis

2 years or older:
0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day for the relief of ocular itching

Use: For the temporary relief of ocular itching due to seasonal allergic conjunctivitis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

0.4% Ophthalmic Solution: Safety and efficacy have not been established in patients younger than 3 years.

0.45% Ophthalmic Solution: Safety and efficacy have not been established in patients younger than 18 years.

0.5% Ophthalmic Solution: Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements:

• Protect from light; store 0.45% vials in the pouch.

• This drug may be administered in conjunction with other topical ophthalmic drugs such as alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, and mydriatics.
• If more than one topical ophthalmic drug is being used, each one should be administered at least 5 minutes apart.

• Avoid allowing the tip of the bottle to contact the eye or surrounding structures to avoid contamination.
• Avoid wearing contact lenses when using this drug.
• To avoid cross-contamination, use 1 bottle for each eye following bilateral ocular surgery; the same bottle of topical eye drops should not be used for both eyes.
• Seek medical attention if you develop an intercurrent ocular condition (e.g., trauma or infection) or have ocular surgery.
• Slowed or delayed healing may occur while using this drug.