Usual Adult Dose for Hypertension

Usual dose: 2.5 mg orally once daily
Maximum dose: 5 mg orally once daily

Comments:

• Adjust dose according to blood pressure goals.
• Wait 7 to 14 days between dose adjustments; if needed, may titrate more rapidly if patient is assessed frequently.

Usual Pediatric Dose for Hypertension

6 to 17 years old: 1.25 to 2.5 mg orally once daily

Comments:

• Doses over 2.5 mg per day have not been studied in pediatric patients.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

• A lower initial dose of 1.25 mg orally once a day may be required in hepatic impairment.
• Titrate slowly in severe hepatic impairment.

Dose Adjustments

Small, fragile, or elderly patients may be started on 1.25 mg orally once a day.

• This dose may be used when adding this drug to other antihypertensives.

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to amlodipine

Dialysis

Data not available