Parenteral:
0.2 mg IM after delivery of the placenta or during the puerperium; may be repeated at intervals of 2 to 4 hours as required
Orally:
0.2 mg orally 3 or 4 times a day for a maximum of 1 week during the puerperium
Comments:
Under full obstetric supervision, this drug may be given parenterally during the second stage of labor following delivery of the anterior shoulder.
IV administration should be avoided unless administration is considered life-saving; IV dosing is the same as IM, give IV slowly over at least 60 seconds
Uses:
For routine management of uterine atony, hemorrhage and subinvolution of the uterus following delivery of the placenta.
For control of uterine hemorrhage in the second stage of labor following delivery of the anterior shoulder.
Renal Dose Adjustments
Use caution
Liver Dose Adjustments
Use caution
Precautions
CONTRAINDICATIONS:
Hypersensitivity
Hypertension
Toxemia
Pregnancy
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
For oral and IM administration; avoid intra-arterial or periarterial administration
Routine IV administration should be avoided because of the possibility of sudden hypertensive and cerebrovascular accidents; if administered IV, give slowly over no less than 60 seconds and closely monitor blood pressure
Storage requirements:
Protect from light
General:
Methergine injection should be stored separately from medications intended for neonatal administration to avoid inadvertent administration to newborn infants.
Monitoring:
Monitor BP, especially if IV administration is necessary
