Usual Adult Dose for Allergic Rhinitis

2 sprays (50 mcg in each spray) in each nostril once a day (total daily dose of 200 mcg)

Comments:

• In patients with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis with this drug is recommended 2 to 4 weeks prior to the anticipated start of the pollen season.

• Treatment of nasal symptoms of allergic and perennial rhinitis
• Treatment of nasal congestion associated with seasonal allergic rhinitis
• Prophylaxis of seasonal allergic rhinitis

Usual Adult Dose for Nasal Polyps

2 sprays (50 mcg in each spray) in each nostril twice a day (total daily dose of 400 mcg)

Comments:

• A dose of 2 sprays (50 mcg in each spray) in each nostril once a day (total daily dose of 200 mcg) is also effective in some patients.

Usual Adult Dose for Sinus Symptoms

Implant which is gradually released over time

Comments:

• The implant separates mucosal tissues, provides stabilization of the middle turbinate, prevents obstruction by adhesions, and reduces edema.
• The implant is designed for single patient use only. Do not reprocess or reuse.

Usual Pediatric Dose for Allergic Rhinitis

2 to 11 years:
1 spray (50 mcg in each spray) in each nostril once a day (total daily dose of 100 mcg)

12 years or older:
2 sprays (50 mcg in each spray) in each nostril once a day (total daily dose of 200 mcg)

Comments:

• In patients with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis with this drug is recommended 2 to 4 weeks prior to the anticipated start of the pollen season.

• Treatment of nasal symptoms of seasonal and perennial allergic rhinitis
• Treatment of nasal congestion associated with seasonal allergic rhinitis
• Prophylaxis of seasonal allergic rhinitis in patients 12 years of age and older

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to any of the ingredients

• Safety and efficacy for allergic rhinitis have not been established in patients younger than 2 years.
• Safety and efficacy for nasal polyps have not been established in patients younger than 18 years.
• Safety and efficacy of the implant have not been established in patients younger than 18 years.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer the nasal spray by the intranasal route only. Shake well before each use.
• Prior to initial use of nasal spray, the pump should be primed by actuating ten times or until a fine spray appears.
• The pump may be stored unused for up to 1 week without repriming. If unused for more than 1 week, reprime by actuating two times, or until a fine spray appears.

• US: Do not use the implant if the package is open or damaged.
• Protect from light
• Do not freeze
• The bottle should be discarded after the labeled number of sprays or within 2 months of first use.