Prior to Initiation of MYFEMBREE

• Exclude pregnancy [see Contraindications (4)].
• Discontinue hormonal contraceptives [see Warnings and Precautions (5.8)].

Recommended Dosage

• Take one tablet of MYFEMBREE orally once daily at approximately the same time, with or without food [see Clinical Pharmacology (12.3)].
• Start MYFEMBREE as early as possible after the onset of menses but no later than seven days after menses has started.
• The recommended total duration of treatment with MYFEMBREE is 24 months [see Indications and Usage (1.3) and Warnings and Precautions (5.2)].

Missed Dose

Take the missed dose of MYFEMBREE as soon as possible the same day and then resume regular dosing the next day at the usual time.

Dosage Modification for Concomitant Use with P-gp Inhibitors

Avoid concomitant use of MYFEMBREE with oral P-gp inhibitors. If concomitant use is unavoidable, take MYFEMBREE first and separate dosing by at least 6 hours [see Drug Interactions (7.1) and Clinical Pharmacology (12.3)].