Drug Detail:Penciclovir topical (Penciclovir topical [ pen-sye-kloe-veer-top-ik-al ])
Drug Class: Topical antivirals
Usual Adult Dose for Herpes Simplex Labialis
Apply cream to affected area every 2 hours while awake
Duration of therapy: 4 days
Comments: Treatment should begin as early as possible (i.e., during the prodrome or when lesions appear).
Use: For the treatment of recurrent herpes labialis (cold sores)
Usual Pediatric Dose for Herpes Simplex Labialis
12 years or older: Apply cream to affected area every 2 hours while awake
Duration of therapy: 4 days
Comments: Treatment should begin as early as possible (i.e., during the prodrome or when lesions appear).
Use: For the treatment of recurrent herpes labialis (cold sores)
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For external use only; only use on herpes labialis on the lips and face.
- Do not apply to mucous membranes; use particular care to avoid applying in or near the eyes.
- Apply a layer of this drug to cover only the cold sore area (or area of tingling [or other symptoms] before appearance of cold sore); rub in until cream disappears.
Storage requirements:
- Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
Patient advice:
- Begin treatment at earliest sign of cold sore (e.g., tingling, redness, itching, bump).
- Wash hands before and after applying this drug.