Drug Detail:Pin-away (Pyrantel [ pie-ran-tell ])
Drug Class: Anthelmintics
Usual Adult Dose for Enterobiasis
11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for E vermicularis (pinworm) infection
- This dose should be repeated in 2 weeks.
- Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
- Current guidelines should be consulted for additional information.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for E vermicularis (pinworm) infection
- This dose should be repeated in 2 weeks.
- Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
- Current guidelines should be consulted for additional information.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
Some Experts Recommend: 11 mg/kg base orally once a day for 3 days
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for A duodenale and N americanus
- Current guidelines should be consulted for additional information.
Usual Adult Dose for Trichostrongylosis
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended for Trichostrongylus infection
- Current guidelines should be consulted for additional information.
Usual Adult Dose for Moniliformis Infection
Some Experts Recommend: 11 mg/kg base orally every 2 weeks for 3 doses
Comments:
- Recommended for Moniliformis moniliformis infection
- Current guidelines should be consulted for additional information.
Usual Pediatric Dose for Enterobiasis
2 years or older: 11 mg/kg base once as a single dose
Maximum dose: 1 g/dose
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for E vermicularis (pinworm) infection
- This dose should be repeated in 2 weeks.
- Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
- Current guidelines should be consulted for additional information.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
2 years or older: 11 mg/kg base once as a single dose
Maximum dose: 1 g/dose
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for E vermicularis (pinworm) infection
- This dose should be repeated in 2 weeks.
- Since family members are usually infected, the entire household should be treated; retreatment after 14 to 21 days may be necessary.
- Current guidelines should be consulted for additional information.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
Some Experts Recommend: 11 mg/kg base orally once a day for 3 days
Maximum dose: 1 g/dose
Comments:
- Recommended as a regimen for A duodenale and N americanus
- Current guidelines should be consulted for additional information.
Usual Pediatric Dose for Trichostrongylosis
Some Experts Recommend: 11 mg/kg base orally once as a single dose
Maximum dose: 1 g/dose
Comments:
- Recommended for Trichostrongylus infection
- Current guidelines should be consulted for additional information.
Usual Pediatric Dose for Moniliformis Infection
Some Experts Recommend: 11 mg/kg base orally every 2 weeks for 3 doses
Comments:
- Recommended for M moniliformis infection
- Current guidelines should be consulted for additional information.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Comments:
- According to manufacturers, this drug should not be used in patients with liver disease unless directed by a physician.
Precautions
CONTRAINDICATIONS: None
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Dose expressed as pyrantel base.
Administration advice:
- Can administer at any time of day, with or without meals; may administer alone or with milk or juice
- Can mix the oral suspension with milk or fruit juice
- Shake oral suspension well before use.
Storage requirements:
- Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
- Do not freeze.
General:
- Pyrantel pamoate 144 mg is equivalent to 50 mg pyrantel base.
- Use of a laxative is not necessary before, during, or after administration of this drug.
Patient advice:
- Read the package insert/product information carefully before use.
- Administer only according to directions; do not exceed recommended dose unless directed by physician.
- Administer 1 time as a single dose; do not repeat treatment unless directed by physician.
Frequently asked questions
- Pyrantel - what is the dosage for cats and kittens?