Usual Adult Dose for Graves' Ophthalmopathy

Initial dose: 10 mg/kg intravenously
Maintenance dose: 20 mg/kg intravenously every 3 weeks for 7 additional infusions

Use: Treatment of thyroid eye disease

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.
This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer diluted solution over 90 minutes for the first 2 infusions; if well tolerated may reduce infusion time to 60 minutes for remaining infusions (if not well tolerated, continue 90 minute infusions).
• Do not administer via intravenous push or bolus.

• Refrigerate; do not freeze.
• Protect from light.