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No, you should NOT take Trelegy and Symbicort together due to the risk of dangerous and possibly fatal...

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Symbicort (generic name: budesonide and formoterol) contains an inhaled corticosteroid (“steroid”)...

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Budesonide and formoterol (inhalation) Uses, Side Effects & Warnings

Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Jul 10, 2023 Additional Content by TheMediTary.Com

Generic name: budesonide and formoterol [ bue-des-oh-nide, for-moe-ter-ol-fue-ma-rate ]

Drug class: Bronchodilator combinations

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Symbicort, Budesonide and formoterol (inhalation)

What is Budesonide and formoterol (inhalation)?

Uses for budesonide and formoterol

Budesonide and formoterol combination is used to help control the symptoms of asthma and improve lung function. It is used when a patient's asthma has not been controlled sufficiently on other asthma medicines, or when a patient's condition is so severe that more than one medicine is needed every day.

Budesonide and formoterol combination is also used as long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. This medicine helps improve and reduce the number of flare-ups of the symptoms of COPD.

Inhaled budesonide belongs to the family of medicines known as corticosteroids (cortisone-like medicines). It works by preventing inflammation (swelling) in the lungs that causes an asthma attack.

Formoterol belongs to the family of medicines known as long-acting bronchodilators. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, and trouble breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Before using budesonide and formoterol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Symbicort Aerosphere® inhaler in the pediatric population. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Symbicort® inhaler in children 6 years of age and older. However, safety and efficacy have not been established in children younger than 6 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Symbicort Aerosphere® inhaler in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Symbicort® inhaler in the elderly. However, elderly patients with heart problems may require special caution when receiving budesonide and formoterol combination.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Bepridil
Cisapride
Desmopressin
Dronedarone
Levoketoconazole
Mesoridazine
Pimozide
Piperaquine
Rotavirus Vaccine, Live
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acebutolol
Aceclofenac
Acemetacin
Adagrasib
Alfuzosin
Amineptine
Amiodarone
Amisulpride
Amitriptyline
Amitriptylinoxide
Amoxapine
Amtolmetin Guacil
Anagrelide
Apomorphine
Aripiprazole
Aripiprazole Lauroxil
Arsenic Trioxide
Asenapine
Aspirin
Astemizole
Atazanavir
Atenolol
Azithromycin
Balofloxacin
Bedaquiline
Belzutifan
Bemetizide
Bemiparin
Bendroflumethiazide
Benzthiazide
Besifloxacin
Betaxolol
Bisoprolol
Boceprevir
Bromfenac
Bufexamac
Bumetanide
Buprenorphine
Bupropion
Buserelin
Carteolol
Carvedilol
Celecoxib
Celiprolol
Ceritinib
Chloroquine
Chlorothiazide
Chlorpromazine
Chlorthalidone
Choline Salicylate
Ciprofloxacin
Citalopram
Clarithromycin
Clofazimine
Clomipramine
Clonixin
Clopamide
Clothiapine
Clozapine
Cobicistat
Conivaptan
Crizotinib
Cyclobenzaprine
Cyclopenthiazide
Cyclosporine
Cyclothiazide
Dabrafenib
Darunavir
Dasatinib
Degarelix
Delamanid
Desipramine
Deslorelin
Deutetrabenazine
Dexibuprofen
Dexketoprofen
Dexmedetomidine
Diazoxide
Dibenzepin
Diclofenac
Diflunisal
Dipyrone
Disopyramide
Dofetilide
Dolasetron
Domperidone
Donepezil
Doxepin
Droperidol
Droxicam
Duvelisib
Ebastine
Efavirenz
Encorafenib
Enoxacin
Entrectinib
Eribulin
Erythromycin
Escitalopram
Esmolol
Ethacrynic Acid
Etodolac
Etofenamate
Etoricoxib
Etozolin
Famotidine
Fedratinib
Felbamate
Felbinac
Fenoprofen
Fepradinol
Feprazone
Fexinidazole
Fingolimod
Flecainide
Fleroxacin
Floctafenine
Fluconazole
Flufenamic Acid
Flumequine
Fluoxetine
Flurbiprofen
Foscarnet
Fosnetupitant
Fosphenytoin
Fostemsavir
Furosemide
Galantamine
Gatifloxacin
Gemifloxacin
Glasdegib
Gonadorelin
Goserelin
Granisetron
Halofantrine
Haloperidol
Histrelin
Hydrochlorothiazide
Hydroflumethiazide
Hydroquinidine
Hydroxychloroquine
Hydroxyzine
Ibuprofen
Ibutilide
Idelalisib
Iloperidone
Imipramine
Indapamide
Indinavir
Indomethacin
Inotuzumab Ozogamicin
Isocarboxazid
Itraconazole
Ivabradine
Ivosidenib
Ketoconazole
Ketoprofen
Ketorolac
Labetalol
Lapatinib
Larotrectinib
Lefamulin
Lenacapavir
Lenvatinib
Leuprolide
Levobunolol
Levofloxacin
Linezolid
Lofepramine
Lofexidine
Lomefloxacin
Lopinavir
Lorlatinib
Lornoxicam
Loxoprofen
Lumacaftor
Lumefantrine
Lumiracoxib
Lutetium Lu 177 Dotatate
Macimorelin
Mavacamten
Meclofenamate
Mefenamic Acid
Mefloquine
Melitracen
Meloxicam
Methacholine
Methadone
Methotrimeprazine
Methyclothiazide
Methylene Blue
Metipranolol
Metolazone
Metoprolol
Metronidazole
Mifepristone
Mirtazapine
Mizolastine
Mobocertinib
Moricizine
Morniflumate
Moxifloxacin
Nabumetone
Nadifloxacin
Nadolol
Nadroparin
Nafarelin
Naproxen
Nebivolol
Nefazodone
Nelfinavir
Nepafenac
Netupitant
Niflumic Acid
Nilotinib
Nimesulide
Nimesulide Beta Cyclodextrin
Nirmatrelvir
Norfloxacin
Nortriptyline
Octreotide
Ofloxacin
Olanzapine
Olutasidenib
Omaveloxolone
Ondansetron
Opipramol
Osilodrostat
Osimertinib
Oxaliplatin
Oxaprozin
Oxprenolol
Oxyphenbutazone
Ozanimod
Pacritinib
Paliperidone
Panobinostat
Papaverine
Parecoxib
Paroxetine
Pasireotide
Pazopanib
Pazufloxacin
Pefloxacin
Penbutolol
Pentamidine
Perphenazine
Phenelzine
Phenobarbital
Phenylbutazone
Piketoprofen
Pimavanserin
Pindolol
Pipamperone
Piretanide
Piroxicam
Pirtobrutinib
Pitolisant
Polythiazide
Ponesimod
Posaconazole
Pranoprofen
Primidone
Probucol
Procainamide
Procarbazine
Prochlorperazine
Proglumetacin
Promethazine
Propafenone
Propranolol
Propyphenazone
Proquazone
Protriptyline
Prulifloxacin
Quetiapine
Quinethazone
Quinidine
Quinine
Quizartinib
Ranolazine
Rasagiline
Relugolix
Ribociclib
Risperidone
Ritlecitinib
Ritonavir
Rofecoxib
Rufloxacin
Safinamide
Salicylic Acid
Salsalate
Saquinavir
Sargramostim
Selegiline
Selpercatinib
Sertindole
Sertraline
Sevoflurane
Siponimod
Sodium Phosphate
Sodium Phosphate, Dibasic
Sodium Phosphate, Monobasic
Sodium Salicylate
Solifenacin
Somatrogon-ghla
Sorafenib
Sotalol
Sparfloxacin
Sulindac
Sulpiride
Sultopride
Sunitinib
Tacrolimus
Tamoxifen
Telaprevir
Telavancin
Telithromycin
Tenoxicam
Tetrabenazine
Tianeptine
Tiaprofenic Acid
Timolol
Tolfenamic Acid
Tolmetin
Tolterodine
Toremifene
Torsemide
Tosufloxacin
Tranylcypromine
Trazodone
Trichlormethiazide
Triclabendazole
Trimipramine
Triptorelin
Trofinetide
Valdecoxib
Vandetanib
Vardenafil
Vemurafenib
Venlafaxine
Vilanterol
Vinflunine
Voclosporin
Voriconazole
Vorinostat
Xipamide
Zotepine
Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Auranofin
Erythromycin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Grapefruit Juice

Proper use of budesonide and formoterol

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Do not stop using this medicine without telling your doctor. To do so may make your condition worse.

Inhaled fluticasone and salmeterol is used to prevent asthma attacks and treat chronic obstructive pulmonary disease (COPD). It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor.

This medicine comes with a patient information leaflet or patient instructions. Read the directions carefully before using this medicine. If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor or pharmacist to show you what to do. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.

In order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.

When you use the Symbicort® inhaler for the first time, or if you have not used it for 7 days or longer, or if the inhaler has been dropped, it may not deliver the right amount of medicine with the first inhalation. Therefore, before using the inhaler, prime it by spraying the medicine 2 times into the air away from the face, and shaking it well for 5 seconds before each spray.

To use the Symbicort® inhaler:

Take the inhaler out of the moisture-protective foil pouch before you use it for the first time.
Do not use the inhaler for this medicine with any other medicine.
Prime the inhaler before use by shaking the inhaler well for 5 seconds and then releasing a test spray. Once again, shake the inhaler and release a second test spray.
Breathe out to the end of a normal breath (exhale). Do not breathe into the inhaler.
Put the mouthpiece fully into your mouth and close your lips around it. Do not block the mouthpiece with your teeth or tongue.
While pressing down firmly and fully on the grey top of the inhaler, breathe in through your mouth as deeply as you can until you have taken a full deep breath.
Hold your breath and remove the mouthpiece from your mouth. Continue holding your breath for as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.
Release your finger from the grey top and then turn your head away from the inhaler. Breathe out slowly to the end of a normal breath. Do not breathe into the inhaler.
Shake the inhaler again for 5 seconds and take the second inhalation following exactly the same steps you used for the first inhalation.
Replace the mouthpiece cover after using the medicine.
Gargle and rinse your mouth with water after each dose. This will help prevent hoarseness, throat irritation, and infection in the mouth. Do not swallow the water after rinsing.
Clean the inhaler every 7 days by wiping the mouthpiece with a dry cloth. Do not put the inhaler into water or try to take it apart. However, you must use a new inhaler with each refill of your medicine.

The dose counter at the top of the Symbicort® inhaler will turn yellow when the inhaler has 20 or fewer doses left. Throw the inhaler when it reaches 0, or if it has been 3 months since you last opened the foil pouch.

When you use the Symbicort Aerosphere® inhaler for the first time, it may not deliver the right amount of medicine with the first puff. Therefore, before using the inhaler, prime it by spraying the medicine 4 times into the air away from the face, and shaking it well before each spray. If you have not used it for 7 days or longer or if you've dropped it, re-prime by spraying the medicine 2 times into the air away from the face, and shaking it well before each spray.

To use the Symbicort Aerosphere® inhaler:

This medicine comes in a sealed foil pouch. Do not open the foil pouch until you are ready to use a dose of this medicine.
Once opened, remove the inhaler from the pouch.
Take the cap off the mouthpiece. Check the mouthpiece to make sure it is clear.
Press the center of the dose indicator all the way down and release it. You may hear a soft click from the dose indicator as it counts down during use.
To inhale this medicine, breathe out fully and try to get as much air out of your lungs as possible. Put your lips tightly around the mouthpiece and breathe in quickly and deeply until the canister stops moving in the actuator and a puff of medicine has been released.
Remove the inhaler from your mouth and hold your breath for as long as is comfortable, and then breathe out slowly through your nose.
Rinse your mouth with water after each dose. This will help prevent infection in the mouth. Do not swallow the water after rinsing.
Clean the actuator at least once a week with warm water for 30 seconds. Shake off the excess water. Let the actuator air-dry overnight. Do not let the canister get wet.

The dose display window of the Symbicort Aerosphere® inhaler will turn red when the inhaler has 20 or fewer doses left. Throw the inhaler when it reaches 0, or if it has been 3 months since you last opened the foil pouch.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation dosage form (aerosol):
- For preventing an asthma attack:
  - Adults and children 12 years of age and older—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 80 or 160 micrograms (mcg) of budesonide and 4.5 mcg of formoterol.
  - Children 6 to 11 years of age—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 80 mcg of budesonide and 4.5 mcg of formoterol.
  - Children younger than 6 years of age—Use and dose must be determined by your child's doctor.
- For treatment and prevention of worsening attacks of COPD:
  - Adults—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 160 micrograms (mcg) of budesonide and 4.8 mcg of formoterol.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the inhaler with the mouthpiece down.

Warnings

It is very important that your doctor check the progress of you or your child at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.

Although this medicine decreases the number of asthma episodes, it may increase the chances of a severe asthma attack when they do occur. Be sure to read about these risks in the patient information leaflet and talk to your doctor about any questions or concerns that you have.

This medicine should not be used if you are having a sudden COPD attack, or if symptoms of COPD attack has already started. Your doctor will give you a short-acting inhaler to use for this condition. If the short-acting inhaler is not working, tell your doctor right away.

Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.

Talk to your doctor or get medical care right away if:

Your symptoms do not improve after using this medicine for a few days or if they become worse.
Your short-acting inhaler does not seem to be working as well as usual and you need to use it more often.

Do not use this medicine together with other inhaled medicines for COPD, including arformoterol (Brovana®), formoterol (Foradil®, Perforomist®), indacaterol (Arcapta® Neohaler®), olodaterol, salmeterol (Serevent®), or vilanterol.

Do not change your dose or stop using your medicine without first asking your doctor.

You may get infections more easily while using this medicine. Tell your doctor right away if you or your child have been exposed to someone with chickenpox or measles.

This medicine may cause fungus infection of the mouth or throat (thrush). Tell your doctor right away if you or your child have white patches in the mouth or throat, or pain when eating or swallowing.

Patients with COPD may be more likely to have pneumonia when taking this medicine. Check with your doctor if you start having increased sputum (spit) production, change in sputum color, fever, chills, increased cough, or an increase in breathing problems.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you or your child have more than one of these symptoms while you are using this medicine: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

This medicine may cause paradoxical bronchospasm, which may be life-threatening. Check with your doctor right away if you or your child are having a cough, difficulty with breathing, or wheezing.

If you or your child develop a skin rash, hives, or any allergic reaction to this medicine, check with your doctor right away.

This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.

This medicine may cause children to grow more slowly than usual. Talk to your child's doctor if you have any concerns.

This medicine may cause heart or blood vessel problems, including heart rhythm problems. Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain.

Call your doctor right away if blurred vision, difficulty in reading, seeing halos around lights, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

This medicine may affect blood sugar and potassium levels. If you notice a change in the results of your blood or urine sugar or potassium tests or if you have any questions, check with your doctor.

Your doctor may want you to carry a medical identification (ID) card stating that you or your child are using this medicine and that you may need additional medicine during times of emergency, a severe asthma attack or other illness, or unusual stress.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

How should I use Budesonide and formoterol (inhalation)

In order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.

To use the Symbicort® inhaler:

Take the inhaler out of the moisture-protective foil pouch before you use it for the first time.
Do not use the inhaler for this medicine with any other medicine.
Prime the inhaler before use by shaking the inhaler well for 5 seconds and then releasing a test spray. Once again, shake the inhaler and release a second test spray.
Breathe out to the end of a normal breath (exhale). Do not breathe into the inhaler.
Put the mouthpiece fully into your mouth and close your lips around it. Do not block the mouthpiece with your teeth or tongue.
While pressing down firmly and fully on the grey top of the inhaler, breathe in through your mouth as deeply as you can until you have taken a full deep breath.
Hold your breath and remove the mouthpiece from your mouth. Continue holding your breath for as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.
Release your finger from the grey top and then turn your head away from the inhaler. Breathe out slowly to the end of a normal breath. Do not breathe into the inhaler.
Shake the inhaler again for 5 seconds and take the second inhalation following exactly the same steps you used for the first inhalation.
Replace the mouthpiece cover after using the medicine.
Gargle and rinse your mouth with water after each dose. This will help prevent hoarseness, throat irritation, and infection in the mouth. Do not swallow the water after rinsing.
Clean the inhaler every 7 days by wiping the mouthpiece with a dry cloth. Do not put the inhaler into water or try to take it apart. However, you must use a new inhaler with each refill of your medicine.

To use the Symbicort Aerosphere® inhaler:

This medicine comes in a sealed foil pouch. Do not open the foil pouch until you are ready to use a dose of this medicine.
Once opened, remove the inhaler from the pouch.
Take the cap off the mouthpiece. Check the mouthpiece to make sure it is clear.
Press the center of the dose indicator all the way down and release it. You may hear a soft click from the dose indicator as it counts down during use.
To inhale this medicine, breathe out fully and try to get as much air out of your lungs as possible. Put your lips tightly around the mouthpiece and breathe in quickly and deeply until the canister stops moving in the actuator and a puff of medicine has been released.
Remove the inhaler from your mouth and hold your breath for as long as is comfortable, and then breathe out slowly through your nose.
Rinse your mouth with water after each dose. This will help prevent infection in the mouth. Do not swallow the water after rinsing.
Clean the actuator at least once a week with warm water for 30 seconds. Shake off the excess water. Let the actuator air-dry overnight. Do not let the canister get wet.

Dosing

For inhalation dosage form (aerosol):
- For preventing an asthma attack:
  - Adults and children 12 years of age and older—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 80 or 160 micrograms (mcg) of budesonide and 4.5 mcg of formoterol.
  - Children 6 to 11 years of age—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 80 mcg of budesonide and 4.5 mcg of formoterol.
  - Children younger than 6 years of age—Use and dose must be determined by your child's doctor.
- For treatment and prevention of worsening attacks of COPD:
  - Adults—Two puffs in the morning and another 2 puffs in the evening. Each inhalation contains 160 micrograms (mcg) of budesonide and 4.8 mcg of formoterol.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the inhaler with the mouthpiece down.

Budesonide and formoterol (inhalation) Dosage information (more detail)

Before Taking

Allergies

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Symbicort Aerosphere® inhaler in the pediatric population. Safety and efficacy have not been established.

Geriatric

Breast Feeding

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Bepridil
Cisapride
Desmopressin
Dronedarone
Levoketoconazole
Mesoridazine
Pimozide
Piperaquine
Rotavirus Vaccine, Live
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone

Acebutolol
Aceclofenac
Acemetacin
Adagrasib
Alfuzosin
Amineptine
Amiodarone
Amisulpride
Amitriptyline
Amitriptylinoxide
Amoxapine
Amtolmetin Guacil
Anagrelide
Apomorphine
Aripiprazole
Aripiprazole Lauroxil
Arsenic Trioxide
Asenapine
Aspirin
Astemizole
Atazanavir
Atenolol
Azithromycin
Balofloxacin
Bedaquiline
Belzutifan
Bemetizide
Bemiparin
Bendroflumethiazide
Benzthiazide
Besifloxacin
Betaxolol
Bisoprolol
Boceprevir
Bromfenac
Bufexamac
Bumetanide
Buprenorphine
Bupropion
Buserelin
Carteolol
Carvedilol
Celecoxib
Celiprolol
Ceritinib
Chloroquine
Chlorothiazide
Chlorpromazine
Chlorthalidone
Choline Salicylate
Ciprofloxacin
Citalopram
Clarithromycin
Clofazimine
Clomipramine
Clonixin
Clopamide
Clothiapine
Clozapine
Cobicistat
Conivaptan
Crizotinib
Cyclobenzaprine
Cyclopenthiazide
Cyclosporine
Cyclothiazide
Dabrafenib
Darunavir
Dasatinib
Degarelix
Delamanid
Desipramine
Deslorelin
Deutetrabenazine
Dexibuprofen
Dexketoprofen
Dexmedetomidine
Diazoxide
Dibenzepin
Diclofenac
Diflunisal
Dipyrone
Disopyramide
Dofetilide
Dolasetron
Domperidone
Donepezil
Doxepin
Droperidol
Droxicam
Duvelisib
Ebastine
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Budesonide and formoterol (inhalation) side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain
chest tightness
chills
cough
difficulty with breathing
ear congestion
fever
headache
loss of voice
muscle aches
pain or tenderness around the eyes and cheekbones
sneezing
sore throat
stuffy or runny nose
unusual tiredness or weakness

Less common

Bladder pain
bloody or cloudy urine
congestion
cough producing mucus
diarrhea
difficult, burning, or painful urination
dryness of the throat
fast, irregular, pounding, or racing heartbeat or pulse
frequent urge to urinate
general feeling of discomfort or illness
hoarseness
joint pain
loss of appetite
lower back or side pain
nausea
noisy breathing
shakiness in the legs, arms, hands, or feet
shivering
sore mouth or tongue
stomach pain
sweating
tender, swollen glands in the neck
trembling or shaking of the hands or feet
trouble with sleeping
trouble with swallowing
voice changes
vomiting
white patches in the mouth or on the tongue

Rare

Blurred vision
confusion
decreased urine
dizziness or lightheadedness when getting up suddenly from a lying or sitting position
dry mouth
enlarged pupils
fainting
flushed, dry skin
fruit-like breath odor
increased hunger
increased sensitivity of the eyes to light
increased sweating, possibly with fever or cold, clammy skin
increased thirst
increased urination
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
muscle cramps
nervousness
numbness or tingling in the hands, feet, or lips
pounding in the ears
seizures
severe chest pain
severe headache
slow, fast, pounding, or irregular heartbeat or pulse
stiff or sore neck
unexplained weight loss

Incidence not known

Blindness
decreased vision
eye pain
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
tearing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Arm, back, or jaw pain
chest pain or discomfort
darkening of the skin
drowsiness
mental depression
rapid, deep breathing
restlessness
skin rash
stomach cramps

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Stomach discomfort

Less common

Belching
difficulty with moving
heartburn
indigestion
muscle spasms or stiffness
pain in the arms or legs
stomach upset
swollen joints

Rare

Bad, unusual, or unpleasant (after) taste
change in taste
deep or fast breathing with dizziness
fear
hives or welts, itching skin
irritability
large, flat, blue, or purplish patches in the skin
numbness in the feet, hands, and around the mouth
redness of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See more: Budesonide and formoterol (inhalation) Side Effects

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