Emcyt is used to treat metastatic or progressive prostate cancer.

Emcyt may also be used for purposes not listed in this medication guide.

You should not use Emcyt if you have a blood clot, swelling of a vein caused by a blood clot, or if you have ever had an allergic reaction to estradiol or nitrogen mustard.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take Emcyt on an empty stomach, at least 1 hour before or 2 hours after a meal.

Take Emcyt with water, not with milk or other dairy products.

Emcyt doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

It may take up to 90 days before you receive the full benefit of taking Emcyt. Your doctor will determine how long to treat you.

You may need frequent blood tests. Your blood pressure will also need to be checked often.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Emcyt.

Store in the refrigerator, do not freeze.

You should not use Emcyt if you are allergic to estradiol or to nitrogen mustard.

You may not be able to use this medicine if you have a blood clot or swelling of a vein caused by a blood clot.

Tell your doctor if you have ever had:

• a blood clot, stroke, or heart attack;

• diabetes;

• high blood pressure (hypertension);

• heart disease or coronary artery disease (atherosclerosis);

• congestive heart failure;

• migraine headaches;

• epilepsy or other seizure disorder;

• low or high levels of calcium in your blood;

• liver disease;

• kidney disease; or

• a bone disorder such as osteoporosis or Paget's disease.

If a man fathers a baby while using Emcyt, the baby may have birth defects. Use condoms to prevent pregnancy during your treatment. Ask your doctor how long you should continue using condoms after you stop taking this medicine.

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not take Emcyt with milk, milk products, calcium supplements, or calcium-rich foods such as ice cream, yogurt, broccoli, and others.

Avoid using antacids or vitamin/mineral supplements that contain calcium. Calcium can make it harder for your body to absorb Emcyt.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Emcyt may cause serious side effects. Stop using Emcyt and call your doctor at once if you have:

• heart problems--shortness of breath (even with mild exertion), swelling, rapid weight gain, chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;

• signs of a stroke--sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;

• signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or

• signs of a blood clot deep in the body--swelling, warmth, or redness in an arm or leg.

Common side effects of Emcyt may include:

• breast swelling or tenderness;

• impotence;

• nausea, diarrhea, upset stomach;

• swelling, trouble breathing;

• leg cramps; or

• abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Other drugs may affect Emcyt, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.