Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Indapamide treats fluid retention (edema) in people with congestive heart failure. indapamide is also used to treat high blood pressure (hypertension).

Indapamide may also be used for purposes not listed in this medication guide.

You should not use indapamide if you are allergic to sulfa drugs or if you are unable to urinate.

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use indapamide in larger or smaller amounts or for longer than recommended.

Indapamide is usually taken once per day in the morning. Follow your doctor's dosing instructions very carefully.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance.

While using indapamide, you may need frequent medical tests and blood pressure checks. Your blood and urine may both be tested if you have been vomiting or are dehydrated.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Usual Adult Dose for Edema:

Initial dose: 2.5 mg orally once a day.

Usual Adult Dose for Hypertension:

Initial dose: 1.25 mg orally once a day.

You should not use indapamide if you are allergic to it, or if:

• you are unable to urinate; or

• you are allergic to sulfa drugs.

To make sure indapamide is safe for you, tell your doctor if you have:

• cirrhosis or other liver disease;

• kidney disease;

• low levels of potassium or sodium in your blood;

• gout;

• diabetes;

• lupus; or

• if you are on a low-salt diet.

Indapamide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether indapamide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Indapamide is not approved for use by anyone younger than 18 years old.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness.

Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Follow your doctor's directions. They may include a daily exercise program and a low-sodium or low-salt diet, potassium supplements, and increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of an electrolyte imbalance, such as:

• drowsiness, lack of energy, feeling tired;

• leg cramps, muscle weakness or limp feeling;

• severe weakness, loss of coordination, feeling unsteady;

• fast or irregular heartbeats, fluttering in your chest, feeling restless;

• numbness or tingling;

• vomiting, constipation;

• headache, confusion, slurred speech;

• a light-headed feeling, like you might pass out;

• dry mouth, increased thirst; or

• little or no urinating.

Common side effects of indapamide may include:

• dizziness;

• weakness, tiredness;

• back pain, muscle cramps;

• feeling anxious or agitated;

• headache; or

• runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your current medicines and any you start or stop using, especially:

• digoxin, digitalis;

• lithium;

• blood pressure medication; or

• steroids (prednisone and others).

This list is not complete. Other drugs may interact with indapamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly, and blood tests should be done occasionally.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.