By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Miscellaneous GI agents > Livmarli
Miscellaneous GI agents

Livmarli

https://themeditary.com/drug/livmarli-4479.html
Medically Reviewed by Judith Stewart, BPharm TheMediTary.Com | Reviewed: Aug 05, 2023  Additional Content by TheMediTary.Com

Generic name: maralixibat

Drug class: Miscellaneous GI agents

Dosage form: oral solution

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Maralixibat

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Livmarli?

  • Livmarli is a prescription medicine used to treat cholestatic pruritus (itch) in patients with Alagille syndrome 1 year of age and older.
  • It is not known if this medicine is safe and effective in children under 1 year of age.
  • It is not known if this medicine is safe and effective in adults 65 years of age and older.

How should I take Livmarli

Read the Instructions for Use that comes with Livmarli for information about the right way to prepare and take Livmarli.

  • Before you take Livmarli for the first time, talk to your healthcare provider or pharmacist about how to measure your prescribed dose.
  • Take Livmarli exactly as your healthcare provider tells you to.
  • Your healthcare provider may start you on a low dose and then increase the dose, especially if you have not taken Livmarli.
  • Do not change your dose unless your healthcare provider tells you to.
  • Livmarli is taken by mouth, 1 time each day, 30 minutes before your first meal of the day.
  • If you miss a dose and it is:
    • 12 hours or less from the time you usually take Livmarli, take the missed dose as soon as possible. Then take your next dose at the usual time.
    • more than 12 hours from the time you usually take Livmarli, do not take the missed dose. Take your next dose at the usual time.
  • If you take too much or overdose, call your healthcare provider or go to the nearest emergency room right away.
  • If you take a medicine that lowers cholesterol by binding bile acids, such as cholestyramine, colesevelam, or colestipol, take it at least 4 hours before or 4 hours after you take Livmarli. Ask your healthcare provider if you are not sure if you take these medicines.

Dosing information

Usual Adult Dose and Usual Pediatric Dose for Cholestatic Pruritus in Patients with Alagille Syndrome:

- 380 mcg/kg once daily, taken 30 minutes before the first meal of the day. Starting dose is 190 mcg/kg orally once daily, and should be increased to 380 mcg/kg once daily after one week, as tolerated.

Use: cholestatic pruritus in patients with Alagille syndrome (ALGS) 1 year of age and older. 

Detailed Livmarli dosage information
Livmarli Dosage information (more detail)

Before Taking

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems.
  • are pregnant or plan to become pregnant. It is not known if Livmarli will harm your unborn baby. Tell your healthcare provider right away if you think that you are pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if Livmarli passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby if you take Livmarli.
Livmarli pregnancy and breastfeeding warnings (more detail)

Livmarli side effects

Livmarli can cause serious side effects, including:

  • Changes in liver tests. Changes in certain liver tests are common in patients with Alagille syndrome but may worsen during treatment. These changes may be a sign of liver injury and can be serious. Your healthcare provider should do blood tests before starting and during treatment to check your liver function. Tell your healthcare provider right away if you get any signs or symptoms of liver problems, including:
    • nausea or vomiting
    • your skin or the white part of your eye turns yellow
    • dark or brown urine
    • pain on the right side of your stomach (abdomen)
    • loss of appetite
  • Stomach and intestinal (gastrointestinal) problems. Livmarli can cause stomach and intestinal problems, including diarrhea, stomach pain, and vomiting during treatment. Tell your healthcare provider right away if you have any of these symptoms more often or more severely than normal for you.
  • A condition called Fat Soluble Vitamin (FSV) Deficiency caused by low levels of certain vitamins (vitamin A, D, E, and K) stored in body fat. FSV deficiency is common in patients with Alagille syndrome but may worsen during treatment. Your healthcare provider should do blood tests before starting and during treatment.
  • Other common side effects reported during treatment were bone fractures and gastrointestinal bleeding.

Your healthcare provider may change your dose or temporarily or permanently stop treatment if you have certain side effects. These are not all of the possible side effects. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Livmarli Side Effects

What other drugs will affect Livmarli?

Tell your healthcare provider about all medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Livmarli may affect the way some other medicines work, and some other medicines may affect the way Livmarli works.

Especially tell your doctor if you take:

  • certain medicines for high cholesterol - cholestyramine, colesevelam, or colestipol. These medicines least should be taken at least 4 hours before or 4 hours after taking Livmarli.

More about Livmarli (Maralixibat)

Dosage information
Livmarli Side Effects
During pregnancy
Livmarli Prescribing Information
Drug images
Side effects
Drug class: Miscellaneous GI agents

Related treatment guides

Cholestatic Pruritus in Alagille Syndrome
Share this Article
Contents
Uses Warnings Before Taking Dosage Side effects Interactions
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by