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Home > Drugs > Statins > Lovastatin
Statins

Lovastatin

https://themeditary.com/drug/lovastatin-5117.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 11, 2023  Additional Content by TheMediTary.Com

Generic name: lovastatin [ loe-va-sta-tin ]

Drug class: Statins

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Altocor, Altoprev

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Lovastatin (Lovastatin [ loe-va-sta-tin ])-93 576-20 mg-Blue-Round Lovastatin 20 mg (93 576)
  • Lovastatin (Lovastatin [ loe-va-sta-tin ])-93 928-40 mg-Green-Round Lovastatin 40 mg (93 928)
  • Lovastatin (Lovastatin [ loe-va-sta-tin ])-R 635-40 mg-Yellow-Round Lovastatin 40 mg (R 635)
  • Lovastatin (Lovastatin [ loe-va-sta-tin ])-M L19-10 mg-White-Round Lovastatin 10 mg (M L19)
  • View all images

What is Lovastatin?

Lovastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Lovastatin is used to lower the risk of stroke, heart attack, and other heart complications in adults with diabetes, coronary heart disease, or other risk factors.

Lovastatin may also be used for purposes not listed in this medication guide.

Warnings

You should not take lovastatin if you have active liver disease, or if you are pregnant or breastfeeding.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Stop taking lovastatin and tell your doctor at once if you become pregnant.

How should I take Lovastatin

Lovastatin comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet usually is taken once or twice a day with meals. The extended-release tablet usually is taken once a day at bedtime. Take lovastatin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lovastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Your doctor may start you on a low dose of lovastatin and gradually increase your dose, not more than once every 4 weeks.

Continue to take lovastatin even if you feel well. Do not stop taking lovastatin without talking to your doctor.

Dosing information

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Swallow the tablet whole and do not crush, chew, or break it.

It may take up to 4 weeks before your cholesterol levels improve, and you may need frequent blood tests. Even if you have no symptoms, tests can help your doctor determine if lovastatin is effective.

You may need to stop using lovastatin for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Lovastatin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Lovastatin dosage information
Lovastatin Dosage information (more detail)

Before Taking

You should not use lovastatin if you are allergic to it, or if:

  • you are pregnant or breastfeeding; or

  • you have active liver disease.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with lovastatin. Your doctor may change your treatment plan if you also use:

  • nefazodone;

  • an antibiotic--clarithromycin, erythromycin, telithromycin;

  • antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole; or

  • antiviral medicine to treat HIV or hepatitis C--boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, tipranavir.

Tell your doctor if you have ever had:

  • liver disease;

  • muscle pain or weakness;

  • kidney disease;

  • a thyroid disorder; or

  • if you drink large amounts of alcohol.

Lovastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in older adults or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Do not use if you are pregnant. This medicine can harm an unborn baby. Use effective birth control to prevent pregnancy. Stop taking this medicine and tell your doctor at once if you become pregnant.

Do not breastfeed while using this medicine.

Lovastatin is not approved for use by anyone younger than 18 years old.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What special dietary instructions should I follow?

Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Avoid drinking grapefruit juice while taking lovastatin.

What should I avoid while using Lovastatin?

Avoid eating foods high in fat or cholesterol, or lovastatin will not be as effective.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Grapefruit may interact with lovastatin and lead to unwanted side effects. Avoid the use of grapefruit products.

Lovastatin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Lovastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.

Also call your doctor at once if you have:

  • muscle weakness in your hips, shoulders, neck, and back;

  • trouble lifting your arms, trouble climbing or standing;

  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or

  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects of lovastatin may include:

  • infections;

  • headache; or

  • accidental injury.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Lovastatin Side Effects

What other drugs will affect Lovastatin?

Some drugs can increase your risk of serious muscle problems if you take them together with lovastatin. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • cyclosporine;

  • danazol;

  • gemfibrozil, fenofibric acid, fenofibrate; or

  • medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others).

This list is not complete and many other drugs may affect lovastatin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order laboratory tests during your treatment, especially if you develop symptoms of liver damage.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking lovastatin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Lovastatin (Lovastatin [ loe-va-sta-tin ])

Dosage information
Lovastatin Side Effects
Patient tips
During pregnancy
Drug images
Side effects
Drug class: Statins

Patient resources

Lovastatin Extended-Release Tablets
Lovastatin Tablets

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