Other names: Fredrickson Type IIb Hyperlipoproteinemia; Hyperlipoproteinemia, Fredrickson Type IIb
Hyperlipoproteinemia Type IIb has elevated LDL, cholesterol, and triglycerides, due to dysregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase), the rate-controlling enzyme in cholesterol biosynthesis.