Miconazole and zinc oxide topical (for the skin) is a combination antifungal medicine that fights infections caused by fungus.

The ointment form is used to treat diaper rash with yeast infection (candidiasis) in children and babies who are at least 4 weeks old. Miconazole and zinc oxide topical ointment is for use only on diaper rash that has been diagnosed by a doctor.

The spray form is used to treat fungal infections of the skin, such as athlete's foot (tinea pedis), jock itch (tinea cruris), or ringworm (tinea corporis). Miconazole and zinc oxide topical spray is for use by adults and children who are at least 2 years old.

Miconazole and zinc oxide topical should not be used to prevent diaper rash in either children or incontinent adults.

Miconazole and zinc oxide topical may also be used for purposes not listed in this medication guide.

This medicine should not be used to prevent diaper rash.

Use exactly as directed on the label, or as prescribed by your doctor.

Your doctor may perform lab tests to make sure you have the type of infection that this medicine can treat effectively.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Clean and dry the affected area before applying this medicine. You may use a mild soap.

Use the ointment for 1 week, each time you change a diaper. This medicine will not be effective without frequent diaper changes.

Change your child's diapers as soon as they become wet or soiled. Keep the diaper area clean and dry.

Do not use miconazole and zinc oxide topical to prevent diaper rash or you may increase your child's risk of infection that is resistant to treatment. Miconazole and zinc oxide topical ointment is not for use on general diaper rash without a related yeast infection.

Allow the spray to dry completely before you dress. There is no need to rub in the medicine.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.

Do not share this medicine with another person, even if they have the same symptoms you have.

Stop using the medicine and call your doctor if symptoms do not improve, or if they get worse. Diaper rash should start to improve within 1 week of use. Jock itch should improve within 2 weeks, and athlete's foot should improve within 4 weeks. For best results, use this medicine as directed and follow all instructions for keeping the treatment area clean and dry.

Store at room temperature away from moisture and heat. Keep the tube or bottle tightly capped when not in use.

Usual Pediatric Dose for Diaper Rash:

Diaper dermatitis complicated by documented candidiasis:
4 weeks or older: Apply to affected area at each diaper change for 7 days.

You should not use miconazole and zinc oxide topical if you are allergic to miconazole, zinc, dimethicone, mineral oil, petroleum, or lanolin.

Do not use the ointment form of this medicine on a child younger than 4 weeks old.

Ask a doctor before using the topical spray on a child younger than 2 years old.

Tell your doctor if you have ever had:

• a weak immune system caused by disease or by using certain medicines.

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

Since miconazole and zinc oxide topical ointment is used with each diaper change, you are not likely to miss a dose.

If you are using the spray on a schedule, use the medicine as soon as you can. Skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

An overdose of miconazole and zinc oxide topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Avoid covering treated skin areas with tight-fitting, synthetic clothing (such as nylon or polyester clothing, or plastic pants) that does not allow air to circulate to your skin. If you are treating your feet, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet as dry as possible.

Rinse with water if miconazole and zinc oxide topical gets in your eyes.

Avoid using scented or perfumed soaps or lotions to clean the diaper area.

Avoid getting this medication in the mouth or vagina.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

miconazole and zinc oxide topical may cause serious side effects. Stop using miconazole and zinc oxide topical and call your doctor at once if you have:

• severe discomfort, redness, or other irritation of treated skin areas.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.