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Home > Drugs > Ophthalmic glaucoma agents > Omlonti
Ophthalmic glaucoma agents

Omlonti

https://themeditary.com/drug/omlonti-2607.html
Medically Reviewed by Judith Stewart, BPharm TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: omidenepag isopropyl

Drug class: Ophthalmic glaucoma agents

Dosage form: ophthalmic solution

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Omlonti?

Omlonti is a prescription eye drop used for the treatment of glaucoma and ocular hypertension.

Omlonti is the first in a new class of drugs called relatively selective prostaglandin EP2 receptor agonists. It works to reduce elevated pressure in the eye by increasing the drainage of a fluid called aqueous humor.

What is Omlonti used to treat?

Omlonti is used for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Ocular hypertension is the term used to describe elevated pressure in the eye. It can lead to glaucoma and vision loss if left untreated.

Glaucoma is an eye disease caused by fluid buildup behind the eye. It can cause damage to the optic nerve, which can lead to visual field loss and blindness.

Open-angle glaucoma is the most common type of glaucoma. It is caused by a blockage in a special membrane (trabecular meshwork) that prevents the aqueous humor from draining out properly.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Use this medicine exactly as your healthcare provider tells you to use it. Omlonti is only for use in the eye.

If you use this medicine with other eye medicines, you should wait at least 5 minutes between using Omlonti and the other medicines.

If you wear contact lenses, remove your contact lenses before using Omlonti. You should wait 15 minutes after using Omlonti before placing your contact lenses back in your eye.

Call your healthcare provider right away if you develop new eye problems including: an eye injury, eye infection, eye pain, light sensitivity, blurry vision, decreased vision, swelling and redness of the eye, problems with your eyelids, changes in the appearance of your eyes, headache, or eye surgery.

If you develop blurred vision or light sensitivity after using Omlonti, do not drive or operate heavy machinery until the symptoms disappear.

Omlonti can cause color changes in your iris and eyelid and may change the length and color of your eyelashes. 

How should I take Omlonti

Step 1. Wash your hands thoroughly with soap and water. If you cannot wash your hands, you can clean your hands using hand sanitizer.

Step 2. Turn the tamper-evident overcap to the left to open the multidose bottle.

Step 3. Remove the tamper-evident overcap and throw it away.

Step 4. Gently shake the bottle.

Step 5. Turn the inner screw cap to the left to remove it. Do not throw the inner screw cap away.

Step 6. Pull down your lower eyelid with a clean finger. The medicine will go into the space between your lower eyelid and your eye.

Step 7. Tilt your head back and look up.

Step 8. Gently squeeze the multi-dose bottle to release 1 drop of the medicine in your eye. Do not let the tip of the multi-dose bottle touch your eye or any other surfaces. If a drop misses your eye, try again.

Step 9. Blink a few times so that the medicine spreads across your eye.

Step 10. After using Omlonti, gently close your eyelid and press the corner of your eye closest to your nose for 2 minutes.

Step 11. Repeat Step 6 to Step 10 for your other eye if you need to use drops in both eyes. 

Dosing information

Usual Adult Dose for Open-Angle Glaucoma / Ocular Hypertension

- The recommended dosage is one drop in the affected eye(s) once daily in the evening.

Use: the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Detailed Omlonti dosage information
Omlonti Dosage information (more detail)

Before Taking

You should not use this medicine if you are allergic to omidenepag isopropyl.

Tell your doctor if you have ever had swelling or infection in your eye; retinal detachment; or eye surgery or injury affecting the lens of your eye.

Omlonti may cause a gradual change in the color of your eyes or eyelids and lashes. You may also notice increased growth or thickness of your eyelashes. These changes occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.

Tell your doctor if you are pregnant or breastfeeding.

After you remove the Omlonti multi-dose bottle from the carton, make sure the tamper-evident overcap is not broken. If the tamper-evident overcap is broken, Omlonti may not be safe for you to use.

Omlonti pregnancy and breastfeeding warnings (more detail)

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

An overdose of Omlonti is not expected to be dangerous.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Omlonti side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have: eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection); vision changes; or red, swollen, or itchy eyelids.

Omlonti can cause color changes in your iris and eyelid and may change the length and color of your eyelashes. 

Common side effects may include:

  • eye redness
  • sensitivity to light
  • blurred vision
  • dry eye
  • instillation site pain
  • eye pain
  • headache
  • eye irritation
  • visual impairment.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Omlonti Side Effects

What other drugs will affect Omlonti?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

If you use this medicine with other eye medicines, you should wait at least 5 minutes between using Omlonti and the other medicines.

More about Omlonti (Omidenepag isopropyl)

Dosage information
Omlonti Side Effects
During pregnancy
Omlonti Eye Drops Prescribing Information
Drug images
Side effects
Drug class: Ophthalmic glaucoma agents

Related treatment guides

Glaucoma, Open Angle
Glaucoma/Intraocular Hypertension
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