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Home > Drugs > Skeletal muscle relaxants > Orphenadrine
Skeletal muscle relaxants

Orphenadrine

https://themeditary.com/drug/orphenadrine-5243.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 11, 2023  Additional Content by TheMediTary.Com

Generic name: orphenadrine [ or-fen-a-drin ]

Drug class: Skeletal muscle relaxants

Dosage form: oral tablet, extended release (100 mg)

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Norflex

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Orphenadrine (Orphenadrine [ or-fen-a-drin ])-KL 111-100 mg-White-Round Orphenadrine 100 mg (KL 111)
  • Orphenadrine (Orphenadrine [ or-fen-a-drin ])-3358 M-100 mg-White-Round Orphenadrine 100 mg (3358 M)
  • Orphenadrine (Orphenadrine [ or-fen-a-drin ])-2011 G-100 mg-White-Round Orphenadrine 100 mg (2011 G)
  • Orphenadrine (Orphenadrine [ or-fen-a-drin ])-E 22-100 mg-White-Round Orphenadrine 100 mg (E 22)
  • View all images

What is Orphenadrine?

Orphenadrine is a muscle relaxer.

Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Orphenadrine may also be used for purposes not listed in this medication guide.

Warnings

You should not take orphenadrine if you have urination problems, an enlarged prostate, glaucoma, a stomach ulcer or blockage in your digestive tract, trouble swallowing, or myasthenia gravis.

How should I take Orphenadrine

Follow all directions on your prescription label. Do not take orphenadrine in larger or smaller amounts or for longer than recommended.

Orphenadrine may be habit-forming. Never share orphenadrine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Orphenadrine is usually taken 2 times per day, once in the morning and once in the evening. Follow your doctor's dosing instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Orphenadrine is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.

Store orphenadrine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Keep track of the amount of medicine used from each new bottle. Orphenadrine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Dosing information

Usual Adult Dose for Muscle Spasm:

Extended-Release Tablets: 100 mg orally twice a day

Parenteral Injection: 60 mg IV or IM every 12 hours as needed

Use: As an adjunct to rest, physical therapy and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.

Detailed Orphenadrine dosage information
Orphenadrine Dosage information (more detail)

Before Taking

You should not use orphenadrine if you are allergic to it, or if you have:

  • urination problems;

  • an enlarged prostate;

  • glaucoma;

  • a stomach ulcer;

  • a blockage in your stomach or intestines;

  • trouble swallowing; or

  • myasthenia gravis.

To make sure orphenadrine is safe for you, tell your doctor if you have:

  • heart disease;

  • a heart rhythm disorder;

  • coronary artery disease; or

  • if you also use a narcotic (opioid) medication.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether orphenadrine passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Orphenadrine is not approved for use by anyone younger than 18 years old.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I avoid while using Orphenadrine?

orphenadrine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Do not drink alcohol. Dangerous side effects or death can occur.

Orphenadrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Orphenadrine may cause serious side effects. Stop using orphenadrine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • painful or difficult urination;

  • little or no urination;

  • confusion, anxiety, agitation, tremors, hallucinations; or

  • pounding heartbeats or fluttering in your chest.

Common side effects of orphenadrine may include:

  • dizziness, drowsiness, weakness;

  • nausea, vomiting;

  • dry mouth; or

  • constipation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

See more: Orphenadrine Side Effects

What other drugs will affect Orphenadrine?

Taking orphenadrine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with orphenadrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Combination Products

  • Invagesic® (containing Aspirin, Caffeine, Orphenadrine)
  • Norgesic® (containing Aspirin, Caffeine, Orphenadrine)
  • Orphengesic® (containing Aspirin, Caffeine, Orphenadrine)

More about Orphenadrine (Orphenadrine [ or-fen-a-drin ])

Dosage information
Orphenadrine Side Effects
During pregnancy
Drug images
Side effects
Drug class: Skeletal muscle relaxants

Patient resources

Orphenadrine Extended-Release Tablets
Orphenadrine Injection

Related treatment guides

Muscle Spasm
Migraine
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