Generic name: oxybutynin (oral) [ ox-i-bue-ti-nin ]
Drug class: Urinary antispasmodics
Availability: Rx and/or otc
Pregnancy & Lactation: Risk data available
Brand names: Gelnique, Gelnique (transdermal), Oxytrol patch, Ditropan xl, Ditropan xl
What is Oxybutynin?
Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.
Oxybutynin is also used in children at least 6 years old with overactive bladder related to a neurologic condition such as spina bifida.
Warnings
You should not use oxybutynin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.
Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.
This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
There are many other medicines that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.
How should I take Oxybutynin
Oxybutynin comes as a tablet, a syrup, and an extended-release (long-acting) tablet to take by mouth. The tablets and syrup are usually taken two to four times a day. The extended-release tablet is usually taken once a day with or without food. Take oxybutynin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take oxybutynin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the extended-release tablets whole with plenty of water or other liquid. Do not split, chew, or crush the extended-release tablets. Tell your doctor if you or your child cannot swallow tablets.
Use a dose-measuring spoon or cup to measure the correct amount of liquid for each dose, not a household spoon.
Your doctor may start you on a low dose of oxybutynin and gradually increase your dose, not more than once every week.
Oxybutynin may control your symptoms but will not cure your condition. Continue to take oxybutynin even if you feel well. Do not stop taking oxybutynin without talking to your doctor.
You may notice some improvement in your symptoms within the first 2 weeks of your treatment. However, it may take 6–8 weeks to experience the full benefit of oxybutynin. Talk to your doctor if your symptoms do not improve at all within 8 weeks.
Dosing information
Take oxybutynin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Take this medicine with a full glass of water, at the same time each day.
You may take oxybutynin with or without food.
Swallow the extended-release tablet whole and do not crush, chew, or break it.
Measure liquid medicine with the supplied measuring device (not a kitchen spoon).
Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.
Store at room temperature away from moisture and heat.
Before Taking
You should not use oxybutynin if you are allergic to it, or if you have:
-
untreated or uncontrolled narrow-angle glaucoma;
-
a blockage in your digestive tract (stomach or intestines); or
-
if you are unable to urinate.
To make sure you can safely take oxybutynin, tell your doctor if you have ever had:
-
glaucoma;
-
trouble urinating;
-
ulcerative colitis;
-
Parkinson's disease;
-
dementia;
-
a nerve disorder that affects your heart rate, blood pressure, or digestion;
-
myasthenia gravis; or
-
a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Tell your doctor if you are pregnant or breastfeeding.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
What should I avoid while using Oxybutynin?
Avoid driving or hazardous activity until you know how oxybutynin will affect you. Your reactions could be impaired.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease sweating and you may be more prone to heat stroke.
Drinking alcohol with this medicine can increase side effects.
Oxybutynin side effects
Get emergency medical help if you have signs of an allergic reaction to oxybutynin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
-
severe stomach pain or constipation;
-
blurred vision, tunnel vision, eye pain, or seeing halos around lights;
-
little or no urination;
-
painful or difficult urination; or
-
dehydration - dizziness, confusion, feeling very thirsty, less urination or sweating.
Common oxybutynin side effects may include:
-
dizziness, drowsiness;
-
headache;
-
dry mouth; or
-
diarrhea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See more: Oxybutynin Side EffectsWhat other drugs will affect Oxybutynin?
Using oxybutynin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
-
antibiotic, antifungal, or antiviral medicine;
-
bronchodilator asthma medication;
-
cold or allergy medicine (Benadryl and others);
-
medicine to treat overactive bladder;
-
medicine to treat dementia;
-
medicine to treat Parkinson's disease; or
-
medicine to treat stomach problems, motion sickness, or irritable bowel syndrome.
This list is not complete. Other drugs may interact with oxybutynin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
If you are taking the extended-release tablet, you may notice something that looks like a tablet in your stool. This is just the empty tablet shell and does not mean that you did not get your complete dose of medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.