By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Sulfonamides > Sulfamethoxazole and trimethoprim
Sulfonamides

Sulfamethoxazole and trimethoprim

https://themeditary.com/drug/sulfamethoxazole-and-trimethoprim-5556.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 12, 2023  Additional Content by TheMediTary.Com

Generic name: sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ]

Drug class: Sulfonamides

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Bactrim, Bactrim ds (oral), Co-trimoxazole (monograph), Cotrim, Septra

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
  • Sulfamethoxazole and trimethoprim (Sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])-MP 85-800 mg / 160 mg-White-Oval Sulfamethoxazole and trimethoprim 800 mg / 160 mg (MP 85)
  • Sulfamethoxazole and trimethoprim (Sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])-5546 DAN DAN-400 mg / 80 mg-White-Round Sulfamethoxazole and trimethoprim 400 mg / 80 mg (5546 DAN DAN)
  • Sulfamethoxazole and trimethoprim (Sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])-93 089-800 mg / 160 mg-White-Oval Sulfamethoxazole and trimethoprim 800 mg / 160 mg (93 089)
  • Sulfamethoxazole and trimethoprim (Sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])-5547 DAN DAN-800 mg / 160 mg-White-Oval Sulfamethoxazole and trimethoprim 800 mg / 160 mg (5547 DAN DAN)
  • View all images

What is Sulfamethoxazole and trimethoprim?

Sulfamethoxazole and trimethoprim is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.

Sulfamethoxazole and trimethoprim may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

How should I use Sulfamethoxazole and trimethoprim

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Sulfamethoxazole and trimethoprim oral is taken by mouth.

Shake the oral suspension (liquid). Measure a dose with the supplied measuring device (not a kitchen spoon).

Sulfamethoxazole and trimethoprim injection is given in a vein. Be sure you understand how to properly mix this medicine with a liquid (diluent) and how to store the mixture. Ask your doctor or pharmacist if you don't understand how to use an injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.

Mixed medicine must be used within 2 to 6 hours depending on the amount of diluent in the mixture. Follow your doctor's instructions. Do not refrigerate mixed medicine.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Drink plenty of fluids to prevent kidney stones.

Antibiotic medicines can cause diarrhea. Tell your doctor if you have diarrhea that is watery or bloody.

Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Sulfamethoxazole and trimethoprim will not treat a viral infection (flu or a common cold).

You may need blood and urine tests, and this medicine may be stopped based on the results.

Store at room temperature away from moisture, heat, and light. Do not refrigerate.

Detailed Sulfamethoxazole / trimethoprim dosage information
Sulfamethoxazole and trimethoprim Dosage information (more detail)

Before Taking

You should not use sulfamethoxazole and trimethoprim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

  • severe liver disease;

  • kidney disease that is not being treated or monitored;

  • anemia (low red blood cells) caused by folic acid deficiency;

  • a history of low blood platelets after taking trimethoprim or any sulfa drug; or

  • if you take dofetilide.

May cause birth defects. Do not use if you are pregnant. Tell your doctor if you become pregnant.

Do not breastfeed.

This medicine should not be given to a child younger than 2 months old.

Tell your doctor if you have ever had:

  • kidney or liver disease;

  • a folate (folic acid) deficiency;

  • asthma or severe allergies;

  • HIV or AIDS;

  • a thyroid disorder;

  • malnourishment;

  • alcoholism;

  • an electrolyte imbalance (such as low blood sodium or high potassium);

  • porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.

What should I avoid while using Sulfamethoxazole and trimethoprim?

If you use the injection form of sulfamethoxazole and trimethoprim, do not eat or drink anything that contains propylene glycol (an ingredient in many processed foods, soft drinks, and medicines). Dangerous effects could occur.

Sulfamethoxazole and trimethoprim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Sulfamethoxazole and trimethoprim side effects

Get emergency medical help if you have signs of an allergic reaction (hives, cough, chest pain, shortness of breath, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, joint pain, muscle aches, severe weakness, pale skin, unusual bruising, or yellowing of your skin or eyes.

Sulfamethoxazole and trimethoprim may cause serious side effects. Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

  • any skin rash, no matter how mild;

  • yellowing of your skin or eyes;

  • a seizure;

  • new or unusual joint pain;

  • increased or decreased urination;

  • swelling, bruising, or irritation around the IV needle;

  • increased thirst, dry mouth, fruity breath odor;

  • new or worsening cough, fever, trouble breathing;

  • high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;

  • low blood sodium--headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or

  • low blood cell counts--fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects of sulfamethoxazole and trimethoprim may include:

  • nausea, vomiting, loss of appetite; or

  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Sulfamethoxazole and trimethoprim Side Effects

What other drugs will affect Sulfamethoxazole and trimethoprim?

You may need more frequent check-ups or medical tests if you also use medicine to treat depression, diabetes, seizures, or HIV.

Tell your doctor about all your current medicines. Many drugs can affect sulfamethoxazole and trimethoprim, especially:

  • amantadine, digoxin, cyclosporine, indomethacin, leucovorin, methotrexate, procainamide, pyrimethamine;

  • an "ACE inhibitor" heart or blood presure medication (benazepril, enalapril, lisinopril, quinapril, ramipril, and others); or

  • a diuretic or "water pill".

This list is not complete and many other drugs may affect sulfamethoxazole and trimethoprim. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More FAQ

Sulfamethoxazole/Trimethoprim - Can this cause blood in my stools?
Sulfamethoxazole/Trimethoprim - Can you take this for a tooth infection?
How long will it take Sulfamethoxazole/Trimethoprim 800-160 mg Tablets (Generic Bactrim)?
Sulfamethoxazole/Trimethoprim - can I take this medication for absess tooth infection?
View more FAQ

More about Sulfamethoxazole and trimethoprim (Sulfamethoxazole and trimethoprim (oral/injection) [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])

Dosage information
Sulfamethoxazole and trimethoprim Side Effects
Patient tips
During pregnancy
Sulfamethoxazole Trimethoprim Oral Suspension Prescribing Information
Drug images
Side effects
Drug class: Sulfonamides

Patient resources

Sulfamethoxazole and Trimethoprim Tablets
Sulfamethoxazole and Trimethoprim Injection
Sulfamethoxazole and Trimethoprim Suspension

Related treatment guides

Bacterial Infection
Bronchitis
Bacterial Skin Infection
Acne
Share this Article
Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by